Young male using topcial testosterone
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Language Matters

“We use the term male and female to refer to someone’s sex as determined by their chromosomes, and men and women to refer to their gender, unless we quote from nonspecific language.”

Sex and gender can be different between time periods and cultures. Both aspects are acknowledged to exist on a spectrum.

Testosterone is a male hormone that is produced in the testicles. It helps the male body to develop sex organs.

The hormone also helps maintain male features such as muscle strength and mass, facial and body hair, and a deepened voice. Your testosterone levels typically peak in early adulthood and slowly decrease with age.

Topical testosterone is a prescription drug that’s applied to your skin. It’s used to treat hypogonadism, a condition of having low testosterone that can be caused by Klinefelter’s syndrome, primary testicular failure, or undescended testicles among other conditions.

The Food and Drug Administration (FDA) has approved topical testosterone in gel form. However, some people prefer compounded testosterone creams (where a pharmacy mixes testosterone with a creamy base), because they find them easier to use and less likely to be transferred by touch. Otherwise, the effects of gels vs. creams are not very different.

There are different types of testosterone available. Some of the most common types are listed.

Testosterone gels

Testosterone gels are applied directly to your skin, usually in the armpit, upper arm, shoulder, or inner-thigh areas. AndroGel is a common brand name for this medication.

Testosterone creams

While not as common as gel versions, testosterone creams may also be sold in specialty pharmacies. The application instructions are the same for both testosterone gels and creams. No matter which version you use, make sure it’s completely absorbed into your skin to reduce transfer to others.

Testosterone patches

Testosterone replacement therapy may also be applied to the skin via patch form. A new patch is applied daily to your arm, abdomen, back, or thigh. It’s recommended that you rotate the site of application to reduce possible skin irritation.

Topical testosterone is a treatment for hypogonadism that may occur with age. However, such products aren’t intended as a treatment for lower testosterone levels as a result of aging. The FDA strongly advises against the use of topical testosterone for such purposes, due to potential cardiovascular risks associated with these products.

While the data on the relationship between The heart disease is very serious. and testosterone replacement therapy is conflicting, prescription testosterone products may increase the risk of heart attack and stroke. If you have a history of such conditions or are considered at high risk, talk with your doctor about whether topical testosterone is safe for you to use.

Additionally, topical testosterone may not be recommended for males with a history of urinary issues, or for those at high risk for The cancer of the prostrate.. While testosterone is not known to cause The cancer of the prostrate., it may fuel its growth if already present.

You also shouldn’t use topical testosterone if you have:

It can cause unexpected side effects if you use testosterone on a daily basis.

Skin problems

Skin reactions are the most common side effects of testosterone. You can develop a reaction at the application site if you apply testosterone directly to your skin. Symptoms can include:

  • burning
  • It was a bit of a blast.
  • It was itching.
  • There is some There is some soreness..
  • swelling
  • redness
  • There is a rash.
  • Dry skin.
  • There is a problem with the skin

Make sure you apply the medication to the skin. If you have any skin reactions, report them to your doctor.

Urinary changes

Topical testosterone can also affect your urinary tract and may worsen symptoms of benign prostatic hyperplasia (BPH). Some people may need to urinate more than usual, including during the night. You may feel an urgent need to urinate, even when your bladder isn’t full.

Blood in the urine is one of the symptoms. If you have trouble with the urinary tract, talk to your doctor.

Breast changes

Hypogonadism can cause male breasts to grow larger. It is rare, but the use of testosterone can cause changes to the breasts. Your body can form more breast tissue when it changes testosterone into a form of the hormone estrogen. Changes to the breasts can be made.

  • It was tender.
  • There is some There is some soreness..
  • It is a pain.
  • swelling

If you are concerned about changes to your breasts while using testosterone, you should see your doctor.

Feeling out of sorts

You can feel a bit out of sorts when you have testosterone. Symptoms can include feeling dizzy, lightheaded, or faint. Hot flashes and pounding sounds can be caused by testosterone use.

These symptoms can disappear on their own. If they are still a problem, talk to your doctor.

Emotional effects

Most males can tolerate testosterone treatment, but a small number develop emotional side effects from the hormonal changes. These can include:

Emotional side effects can be serious. Discuss any symptoms with your doctor.

Sexual dysfunction

“Testosterone is a key component in a male’s sex drive. In rare cases, testosterone can affect sex life. It may cause problems.”

  • The desire is lost.
  • inability to maintain an erection
  • erections that last a long time.

If you have any of these symptoms, you should call your doctor.

Transfer through touch

It is best to let the medication try before you come in contact with others, as it can cause side effects if you touch it.

Children may develop aggressive behavior, enlarged genitals, and pubic hair. Females may develop unwanted hair growth or There is a problem with the skin. Testosterone transfer is especially dangerous for pregnant people because it can cause birth defects.

“Don’t allow skin-to-skin contact with other people if you are treating a problem. Keep the area covered or wash it well. Don’t allow anyone to touch bedding or clothing that may have been absorbed testosterone from your skin.”

There are more serious risks associated with using testosterone.

Increased cardiovascular risk

The FDA has issued a warning of the potential increased risk of cardiovascular events among people using testosterone products. Be sure to consult with your healthcare professional to discuss any concerns you may have before using.

Increased risk of The cancer of the prostrate.

While more studies are needed in this regard, there is some concern that testosterone products may increase the risk of developing The cancer of the prostrate..

One 2015 review of existing observational studies concluded that the evidence was not strong enough but that larger studies in the future may find different results. A doctor should conduct a The cancer of the prostrate. screening before prescribing testosterone medications.

Risk of venous thromboembolism

Some people who take topical testosterone may also be at an increased risk of developing deep vein thrombosis (DVT) or pulmonary embolism (PE). See a doctor if you experience It is a pain. and warmth in your legs, or if you have unusual The breath was very thin..

Testosterone injections

These medications are injected into your skin by a doctor about every 1 to 2 weeks, although long-acting treatments may be available that only require injections every 10 weeks.

Nasal gel

Testosterone is also available via a nasal gel that’s pumped into each nostril 3 times daily. Aside from the most common side effects of testosterone therapy, some nasal gels may also cause nasal congestion or irritation.

Buccal tablets

Testosterone buccal tablets work via absorption in the gums. These are applied to your gums twice daily.


Another option involves the surgical placement of testosterone pellets under your skin. This procedure is repeated every 3 to 6 months.

If you’re experiencing possible symptoms of hypogonadism, it’s important to see a doctor for an exact diagnosis. Testosterone levels may decrease with age, but some of the associated symptoms, such as fatigue and weight gain, may also be related to other underlying health conditions.

Once a doctor prescribes topical testosterone, they will discuss the potential side effects of the medication with you before use. However, you should seek emergency medical help right away if you experience any of the following:

  • The breath was very thin.
  • chest It is a pain.
  • slurred speech
  • It is a pain. or weakness on one side of your body

Are there long-term effects of topical testosterone?

Yes. Some of the long-term concerns associated with topical testosterone include an increased risk for cardiovascular disease and related events, such as heart attack and stroke. However, the evidence is mixed. A doctor can help you determine whether the potential benefits of topical testosterone outweigh the possible risks.

What drugs react with topical testosterone?

Topical testosterone may interact with corticosteroids, insulin, and oral anticoagulants. Tell your doctor if you take any of these types of medications before starting testosterone replacement therapy.

Can you get topical testosterone over the counter?

Topical testosterone is available by prescription only. While some over-the-counter (OTC) products may claim to increase testosterone levels, these don’t contain the same active ingredients. They may also be unsafe.

Tell your doctor about any herbs or supplements you are taking.

You should only use the drug under the supervision of your doctor.

It may cause side effects other than the ones we have mentioned, so talk with your doctor if you have questions. Some side effects may need medical attention if they clear up on their own. You should report any side effects to your doctor.

If you have any other health conditions, be sure to tell your doctor.

  • There is a disease called diabetes.
  • There are allergies.
  • The cancer of the prostrate.
  • The heart disease is very serious.

Tell them about the OTC and prescription drugs you are taking.