Acromegaly is a rare medical condition that causes bones, organs, and other tissues throughout the body to become larger than usual. It happens when your pituitary gland makes too much growth hormone (GH). The National Institute of Diabetes and Digestive and Kidney Diseases estimates that
Complications from acromegaly include type 2 diabetes, arthritis, and conditions that affect your muscles, cartilage, and bones. Acromegaly can also be a factor in developing heart disease and heart failure.
Acromegaly is associated with a lower life expectancy and higher mortality rate. But your outlook can be more encouraging if doctors diagnose and treat it early. Because acromegaly can lead to heart failure, it’s important to check with a doctor or healthcare professional as soon as symptoms develop.
The excess GH leads to left ventricular hypertrophy. Your heart muscle becomes bigger and thicker with LVH. This can cause your blood pressure to go up.
Regurgitation means the valves don’t close properly between heartbeats, allowing blood to flow backward. Among the complications are high blood pressure. and abnormal heart rhythms, such as atrial fibrillation.
Of all the serious health complications associated with acromegaly, cardiovascular disease is the most serious. According to a
LVH affects your heart’s left ventricle, the chamber that pumps blood out to most of the body. When this happens, your heart isn’t as effective at pumping blood to meet your body’s needs. This causes your blood pressure to increase.
Sphygmomanometer shows that high blood pressure. causes your heart to pump less blood. This makes your heart work harder. That burden can lead to heart failure.
Acromegaly can also cause other complications that contribute to heart failure, such as
During the night, the breathing can be interrupted by the effects of the OSA. The pauses cause your heart to work harder, which leads to a weaker heart muscle and heart failure.
Acromegaly may also contribute to
Changes in the body are what usually precede screening for acromegaly.
- The jaw and brow are changing.
- Feet and hands are swollen.
- skin becoming thicker
If a doctor suspects acromegaly, they may order two different blood tests to determine if your body is producing too much GH. The two screenings are not open to the public.
- Insulin-like growth factor (IGF) test: IGF-1 is a hormone involved in regulating GH in your body. Unlike GH levels, which can change throughout the day, IGF-1 levels tend to remain steady. Higher-than-normal IGF-1 levels suggest you may have acromegaly.
- Oral glucose tolerance test (OGTT): In an OGTT, you swallow a sugary liquid before a medical professional draws your blood. They’ll test your blood every 30 minutes for up to 2 hours to check your GH levels. The sugary liquid normally causes GH levels to dip, but if they remain high, you likely have acromegaly.
Blood tests are used to determine if a heart disease is related to acromegaly.
- HDL (“good”) cholesterol
- LDL (“bad”) cholesterol
- Total cholesterol.
- There are some types of cholesterol.
“Other screenings can look for changes to the heart’s structure.”
- The echocardiogram shows the results.
- The electrocardiogram is alectrocardiogram.
- The stress test is done.
A doctor should also listen to your heart with a stethoscope and check your blood pressure. If any of these screenings or specific symptoms warrant further evaluation, more invasive tests, such as cardiac catheterization, may be appropriate.
The severity of the illness is one of the factors that affects the best treatment. In some cases, treating the underlying acromegaly can help relieve symptoms.
Because acromegaly is often due to a tumor in the pituitary gland, surgery to remove the tumor or radiation treatment to shrink the tumor can also halt the progression of symptoms and complications. A
Medications and lifestyle changes are usually necessary to treat heart-related problems associated with acromegaly. You may also need devices or procedures to restore optimal heart function. If you have valve disease, repair or replacement of the affected valve is often a safe and effective solution.
Doctors may treat Arrhythmias. with antiarrhythmic drugs or procedures, such as cardioversion or ablation. A doctor may also prescribe blood thinners if they determine the arrhythmia is a stroke risk.
If you develop heart failure, a doctor may prescribe some drugs.
- antihypertensive drugs to lower blood pressure
- anticoagulants (blood thinners) to reduce clotting complications
- cholesterol-lowering drugs, such as statins
Doctors also treat heart failure with certain devices. An implantable cardioverter defibrillator can help keep a healthy heart rhythm. A left ventricular assist device can act as an artificial pump to increase blood flow out of the heart.
People with acromegaly usually only develop heart failure if their condition goes untreated or is poorly treated for a long time. In such cases, the 5-year mortality rate is about 37.5%.
If doctors diagnose and treat heart failure in its early stages, your outlook is much better.
It is not always possible to prevent acromegaly from leading to heart failure. If you respond to acromegaly symptoms early, work closely with your doctors to treat the condition, and watch your heart health, you can lower the risk of a serious heart problem.
Does acromegaly always lead to heart failure?
Acromegaly causes many medical problems, but heart failure and other heart related problems are not always among them. It is not possible to predict all the health problems that may occur after a doctor makes an initial diagnosis.
Is acromegaly life threatening?
Acromegaly can be life threatening. People who receive an early diagnosis can often start a treatment regimen that reduces symptoms and causes more serious problems.
Does recovery from acromegaly reverse damage to the heart?
“The treatment of acromegaly may stop the damage to the heart. You can’t reverse damage to your heart muscle and valves without surgery. The risk of further damage is lowered by recovery from acromegaly.”
Acromegaly is a rare condition in which your body produces too much growth hormone. Most organs, including the heart, are at risk of having problems because of excessive tissue growth.
Cardiovascular problems are the most common. They include:
- high blood pressure.
- The cardiomyopathy is a disease.
- valve disease
The development of heart failure can be contributed to by all of the above.
A prompt diagnosis and adherence to treatments can lower your risk of acromegaly.