If you have type 2 diabetes, your doctor might suggest Amaryl as a treatment option. It’s a prescription drug used along with exercise and a balanced diet to help manage blood sugar in adults.

You can take a tablet called amaryl. Its active ingredient is glimepiride. (An active ingredient is what makes a drug work.) Glimepiride belongs to a group of drugs called sulfonylureas.

This article describes the dosages of Amaryl, as well as its strengths and how to take it. To learn more about Amaryl, see this in-depth article.

Note: This chart highlights the basics of Amaryl’s dosage. Be sure to read on for more detail.

Recommended starting dosage Maximum dosage
1 gram. once daily or 2 tablets. once daily 8 mg once daily

Please keep in mind that this article covers Amaryl’s standard dosing schedule, which is provided by the drug’s manufacturer. But always follow the dosing instructions your doctor prescribes.

The section describes standard dosage and administration information. Before you start taking this medication, your doctor will review the instructions for you.

What is Amaryl’s form?

You can take a tablet called amaryl.

What strengths does Amaryl come in?

The following strengths are offered by the amaryl tablets.

  • 1 gram.
  • 2 tablets.
  • 4 tablets.

What are the usual dosages of Amaryl?

Your doctor will usually start you with a low dose of the drug. They will adjust it over time to reach the right amount. They will prescribe the smallest dose that best manages your blood sugar.

The information below describes Amaryl dosages for diabetes that are commonly used or recommended. But be sure to take the dosage your doctor prescribes for you. They’ll determine the best dosage to fit your needs.

The recommended starting dosage of Amaryl is 1 mg or 2 tablets. taken once daily. Your doctor will decide which starting dosage is safe for you based on Your age. and how well your kidneys work.

Your doctor will likely test your blood sugar level periodically to check how well Amaryl is working. If this medication is not lowering your blood sugar enough, they’ll increase your dose by 1 mg or 2 tablets. at a time. They’ll do this every few weeks until you reach a dose that works for you.

The maximum daily dose of the drug is 8.

Is Amaryl taken long term?

It is a long-term treatment for Amaryl. If you and your doctor determine that it is safe and effective for you, you will probably take it for a long time.

Dosage adjustments

Certain drugs can affect how well Amaryl works. Let your doctor know all the drugs you take. They may need to adjust your dose.

If you have a good kidneys and are old, your doctor may reduce your dose of the drug to reduce your risk of side effects.

The amount of the drug you are prescribed will depend on a number of factors. These include:

  • The severity of the condition you are treating.
  • Your age.
  • how well your kidneys are working
  • You take other drugs.
  • You may have other conditions.

You can take a tablet called amaryl. It’s recommended that you take it once daily with breakfast or your first meal of the day.

For information on Amaryl expiration, storage, and disposal, see this article.

Accessible drug containers and labels

“If you can’t read the prescription label on your medication, you should tell your doctor or pharmacist. Some pharmacies have labels for medication.”

  • Large print or use of blind.
  • You can use a code on a phone to change the text to sound.

“If your current pharmacy doesn’t offer accessibility features, your doctor or pharmacist may be able to recommend a new pharmacy.”

Let your pharmacist know if you have trouble opening bottles. They may be able to deliver it in a container. They may have tips to make it easier to open the drug container.

If you miss a dose, take it as soon as you remember. If you missed the dose, just take your next dose at regular time, and skip the missed dose.

If you need help remembering to take your dose on time, try using a medication reminder. This can include setting an alarm or downloading a reminder app on your phone.

Do not take more Amaryl than your doctor prescribes. Taking more than this can lead to serious side effects, including severe hypoglycemia (low blood sugar).

Symptoms of overdose

The symptoms of a overdose are similar to low blood sugar. These include:

What to do in case you take too much Amaryl

Call your doctor right away if you think you’ve taken too much Amaryl. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.

The dosages provided by the drug manufacturer are described in the sections above. If your doctor recommends it, they will prescribe the correct amount of the drug.

Remember, you should not change your dosage of Amaryl without your doctor’s recommendation. Only take Amaryl exactly as prescribed. Talk with your doctor if you have questions or concerns about your current dosage. Here are some examples of questions you may want to ask your doctor:

  • Will my dose of the drug be different if I am older?
  • Will my Amaryl dose be affected if I’m taking insulin along with it?
  • Is a lower dose of Amaryl going to reduce my risk of side effects?

If you have type 2 diabetes, you can get tips for managing your condition and more by signing up for Healthline’s online newsletter. You can also join Bezzy T2D, a supportive online community of others living with the same condition.


Will my doctor have to change my medication if I start taking steroids?



It depends. Corticosteroids, such as prednisone (Rayos) and methylprednisolone (Medrol), can make Amaryl less effective. They can also increase your blood sugar for part of the day.

If you’re only taking corticosteroids for a short time, your doctor may not need to adjust your Amaryl dose. But they’ll likely have you check your blood sugar often while taking the steroid and after you stop taking it. They’ll let you know if you should change your Amaryl dosage based on your blood sugar levels.

If you have high blood sugar, your doctor may need to adjust your dose of the medicine.

It is important to tell your doctor and pharmacist about all the drugs you take.

To learn more about Amaryl dosage adjustments specific to your type 2 diabetes treatment, talk with your doctor.

The Healthline Pharmacist TeamAnswers represent the opinions of our medical experts. All content is strictly informational and should not be considered medical advice.

Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.