The drug has warnings. These are the most serious warnings from the FDA. There are warnings about drug effects that may be dangerous.

  • Heart risks warning: This drug is a nonsteroidal anti-inflammatory drug (NSAID). All NSAIDs can increase your risk of heart attack, heart failure, or stroke. This risk increases the longer you use NSAIDs. It also increases if you use high doses. Your risk may be higher if you have risk factors for heart disease, such as high blood pressure. Talk to your doctor before taking celecoxib if you have heart disease.
  • Coronary artery bypass graft warning: Don’t take celecoxib if you will have or have recently had a coronary artery bypass graft, or heart surgery to improve blood flow to your heart. Your risk of heart attack or stroke increases if you take celecoxib to treat pain before or after your surgery.
  • Stomach problems warning: Don’t use celecoxib if you have current stomach bleeding or a history of stomach ulcers. Taking celecoxib increases your risk of stomach bleeding, ulcers, or small holes in the lining of your stomach or intestines, which can be fatal. These may occur at any time without any warning symptoms. If you’re 65 years or older, you’re at higher risk of these problems.
  • Serious skin reactions warning: Taking this drug may cause serious and sometimes deadly skin reactions, including Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). Get immediate medical help if you have signs of red, swollen, blistered, or peeling skin; red or irritated eyes; or sores in your mouth, throat, nose, or eyes.

  1. Celecoxib oral capsule is available as a generic drug and a brand-name drug. Brand name: Celebrex.
  2. You can take a capsule by mouth.
  3. This drug is used to treat a variety of conditions.

Celecoxib oral capsule is a prescription drug that’s available as the brand-name drug Celebrex. It’s also available in a generic version. Generic drugs usually cost less. In some cases, they may not be available in every strength or form as the brand-name version.

You can take a capsule by mouth.

Why it’s used

This drug is used to treat a disease.

  • Rheumatoid arthritis is a disease.
  • Inflammation.
  • Ankylosing spondylitis is a disease.
  • Short-term pain.
  • menstrual issues

How it works

This drug is a part of a class of drugs called NSAIDs. A group of drugs that work in the same way are called a class of drugs. Similar conditions are often treated with these drugs.

NSAID block cyclooxygenase. The chemicals that cause pain and inflammation are produced by the cox. NSAIDs like this one stop the chemicals from forming. This reduces inflammation and pain.

Celecoxib can cause other side effects.

More common side effects

There are more common side effects with celecoxib oral capsule.

  • stomach ache
  • It is a problem of the colon.
  • There is a lot of diarrhea.
  • There is gas.
  • There is a burning sensation in the stomach.
  • nausea
  • vomiting
  • dizziness
  • There is a throbbing head.
  • Respiratory tract infections.

If the effects are mild, they may go away in a few days or weeks. If they are more severe, you should talk to your doctor or pharmacist.

Serious side effects

If you have serious side effects, call your doctor. If you think you are having a medical emergency, call the emergency room. There are serious side effects and their symptoms.

  • There is a heart attack or chest pain.
  • Stroke. Symptoms may include:
    • weakness in one part of your body
    • slurred speech
    • On one side of your face.
    • blurred vision
    • There was a sudden dizziness or trouble walking.
    • very severe There is a throbbing head. with no other cause
  • High blood pressure.
  • Edema. Symptoms may include:
    • swelling in your hands and feet.
    • Unusual weight gain.
  • Bleeding and ulcers in your stomach and intestine. Symptoms may include:
    • There is blood in the urine.
    • vomiting
    • stools were bloody
    • The stools are sticky.
  • Skin reactions include blisters.
  • Allergic reactions. Symptoms may include:
    • It was itching and it was Hives.
    • “It’s swelling of your face or throat.”
  • There are problems with the lysies. Your skin may be yellow or your eyes may be white.
  • There are asthma attacks.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history.

Celecoxib oral capsule may interact with other drugs. Your doctor should be careful with your medications. If you are curious about how this drug might interact with other drugs, you should talk to your doctor or pharmacist.

You can reduce your chances of drug interactions by having all of your prescriptions filled at the same pharmacy. A pharmacist can check for drug interactions.

There are drugs that can cause celecoxib to have an interaction.

Blood thinner, anticoagulant

Combining warfarin and celecoxib raises your risk of bleeding.

Mental health drug

Celecoxib may increase the levels of lithium in your body. Signs of lithium toxicity include slurred speech and tremors.

Blood pressure drugs

Celecoxib may reduce the effects of some blood pressure drugs. These drugs can be examples.

  • ACE is an antiotensin-converting enzyme.
  • Angiotensin II blockers are used.
  • Dehydration.

Transplant drug

Combining cyclosporine and celecoxib raises your risk of kidney damage.

Cancer drugs

Taking celecoxib with certain drugs used to treat cancer raises the risk of side effects from those drugs. These side effects include kidney damage and a decrease in cells that help you fight infection. Examples of these drugs include:

  • methotrexate
  • pemetrexed

Other NSAIDs

NSAID is a non-steroidal anti-Inflammatory drug. It increases your risk of side effects. Other NSAID examples include:

  • Ibuprofen.
  • naproxen
  • A drug called aspirin.

Corticosteroids

celecoxib and prednisone can cause stomach bleeding.

Digoxin

If you take celecoxib with digoxin, you may have increased levels of digoxin in your body. Your doctor may monitor your digoxin levels if you take these drugs together.

Antidepressants

Consuming celecoxib with other drugs increases your risk of stomach bleeding. There are examples of SSRIs and SNRIs.

  • The drug citalopram.
  • Paxil is a drug.
  • sertraline is a drug.
  • venlafaxine is a drug.
  • duloxetine is a drug.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.

This drug has several warnings.

High blood pressure. warning

This drug can cause high blood pressure. If you have high blood pressure, take this medication with caution. Before taking this drug, check your blood pressure.

Asthma warning

If you have asthma, take this drug with care. It could cause narrowing in your airway, which could lead to death. If your asthma gets worse while you take this drug, you should get medical attention.

Allergy warning

This drug can cause a reaction. Symptoms may include:

  • breathing problems
  • “It’s swelling of your tongue or throat.”
  • There are bees.

If you have an allergic reaction, call your doctor or local poison control center right away. If your symptoms are severe, call 911 or go to the nearest emergency room. Don’t take this drug again if you’ve ever had an allergic reaction to it. Taking it again could be fatal (cause death).

Alcohol interaction warning

The risk of stomach bleeding is raised by combining alcohol and celecoxib.

Smoking warning

Smoking while taking celecoxib increases your risk of bleeding.

Warnings for people with certain health conditions

For people with heart disease: If you have a history of heart disease or are at risk for heart disease, you shouldn’t take celecoxib. It raises your risk of blood clots, heart attack, and stroke.

For people with stomach problems: If you have a history of stomach bleeding or ulcers, you’re at greater risk of having another ulcer or bleeding event, which may be fatal.

For people with sulfonamide “sulfa” allergy: If you’re allergic to medications that contain sulfonamide, you shouldn’t take this drug. This drug contains sulfonamide. You may have serious skin reactions. Report any skin rash to your doctor right away.

Warnings for other groups

For pregnant women: Tell your doctor if you’re pregnant or plan to become pregnant. Research in animals has shown adverse effects to the fetus when the mother takes the drug. This drug should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

If you become pregnant while taking this drug, call your doctor.

For women who are breastfeeding: This drug has been shown to pass through breast milk. You and your doctor should decide if you’ll take this drug or breastfeed.

For seniors: This drug has been studied in a small number of people older than 65 years. If you’re 65 years or older, you may have increased risk of stomach problems and kidney failure that may be fatal.

For children: This drug hasn’t been studied in people younger than 2 years.

This information is for the oral capsule. There are no possible dosages or forms included here. How often you take it will depend on your dose and form.

  • Your age.
  • The condition is being treated.
  • How bad is your condition?
  • You have other medical conditions.
  • How do you react to the first dose?

Forms and strengths

Generic: Celecoxib

  • Form: oral capsule
  • Strengths: 50 mg, 100 mg, 200 mg, and 400 mg

Brand: Celebrex

  • Form: oral capsule
  • Strengths: 50 mg, 100 mg, 200 mg, and 400 mg

Dosage for Inflammation.

The adult dosage is 18 years and older.

The typical dose is 200 or 100 in evenly distributed amounts.

The child dosage is between the ages of 0 and 17 years.

There is no safe and effective dosage for this age group.

Dosage for Rheumatoid arthritis is a disease.

The adult dosage is 18 years and older.

The typical dose is 100–200mg taken twice per day.

Child dosage (ages 2 to 17 years), for juvenile Rheumatoid arthritis is a disease.

  • The typical dose for children who weigh 22–55 pounds is 50 percent of their body weight.
  • The typical dose for children who weigh more than 25 lbs is 100 in evenly distributed doses.

The child dosage is between 0 and 1 years.

Dosage has not been established for children younger than 2 years.

Dosage for Ankylosing spondylitis is a disease.

The adult dosage is 18 years and older.

  • The typical dose is 200 or 100 in evenly distributed amounts.
  • “400 imi per day is the maximum your doctor can give if celecoxib isn’t working.”

The child dosage is between the ages of 0 and 17 years.

There is no safe and effective dosage for this age group.

Dosage for Short-term pain.

The adult dosage is 18 years and older.

  • The first 400 IU is the typical dose, followed by a 200 IU dose about 8 hours later.
  • The typical dose is 200mg taken twice per day.

The child dosage is between the ages of 0 and 17 years.

There is no safe and effective dosage for this age group.

Dosage for menstrual issues

The adult dosage is 18 years and older.

  • The first 400 IU is the typical dose followed by a 200 IU dose about 8 hours later.
  • The typical dose is 200mg taken twice per day.

The child dosage is between the ages of 0 and 17 years.

There is no safe and effective dosage for this age group.

Special considerations

People with liver disease: Having liver disease may reduce your ability to clear this drug from your body, which could lead to more side effects. If you have moderate liver disease, your daily dose of celecoxib may be reduced by half. If you have severe liver disease, you shouldn’t take this medication.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. This information is not a substitute for medical advice. Always speak with your doctor or pharmacist about dosages that are right for you.

“Depending on your condition, Celecoxib oral capsule may be used. If you don’t take the drug as prescribed, it can have risks.”

If you stop or miss doses: If you stop taking this drug, miss doses, or don’t take it on schedule, you may experience more pain caused by your condition.

If you take too much: Taking too much increases your risk of experiencing side effects.

What to do if you miss a dose: If you miss your dose, take it as soon as you can. However, if it’s just a few hours until your next dose, skip the missed dose. Never try to catch up by taking two doses at once. This could result in toxic side effects.

How to tell if the drug is working: You may be able to tell this drug is working if you experience less pain.

If your doctor prescribes celecoxib oral capsule, keep these considerations in mind.

General

  • Depending on your dosage, you should take this drug with food. If you take 400 celecoxib twice a day, you should take it with food. If you take 200 celecoxib twice a day, you can take it without food.
  • If you need to open the capsule, you can.
  • If you have trouble swallowing the capsule, you can open it and sprinkle the contents onto a level amount of applesauce. You should eat the applesauce with some water.

Storage

  • Store in a room that is between 20 and 25C. You can store it at temperatures between 59F and 86F.
  • Keep this drug away from the light.
  • “Don’t store this medication in damp areas.”

Refills

A prescription is not replaceable. If you need a new prescription for this medication, you will have to contact your doctor.

Travel

Traveling with your medication.

  • Carry your medication with you. Never put it in a checked bag. It should be in your carry-on bag.
  • “Don’t worry about the machines. They can not hurt your medication.”
  • You may need to show the pharmacy label to the airport staff. You should always carry the original box.
  • “Don’t leave this medication in the car or put it in the glove compartment. It is very hot or very cold when this is happening.”

Clinical monitoring

Your doctor will check your blood pressure before and during treatment. Your doctor may do blood tests to make sure your organs are functioning well during treatment.

Sun sensitivity

If you take celecoxib, you may be more sensitive to sunlight. Protect yourself from the sun.

  • Wear clothes that protect you from the sun.
  • SPF 15 or higher is recommended.
  • Limit your time in the sun.
  • Avoid tanning beds.

Insurance

This drug is required by many insurance companies. Your insurance company will pay for the prescription if your doctor gets approval from them.

There are other drugs that can be used to treat your condition. Some may be more suitable for you. Talk to your doctor about alternatives.

Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up-to-date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or other healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.