Dupixent Injection Dosage
If you have certain inflammatory conditions, your doctor might suggest Dupixent (dupilumab) as a treatment option for you.
Dupixent is a prescription medication.
- moderate to severe asthma in adults and children ages 6 years and older
- (eczema) in adults and children ages 6 years and older
- chronic rhinosinusitis with nasal polyps in adults
“Dupixent is a single-dose prefilled pen and a single-dose prefilled syringe. You can get your Dupixent injections at your doctor’s office. In some cases, your doctor may show you how to give yourself injections at home. To learn how Dupixent is used, see the below question.”
This article describes the dosages of Dupixent, including its forms, strengths, and how to take the drug. To learn more about Dupixent, see this in-depth article.
Note: This article covers typical Dupixent dosages from the drug’s manufacturer. But when using Dupixent, always take the dosage that your doctor prescribes.
The section covers the common dosage information.
“Depending on your situation, you can either get a dose at your doctor’s office or get injections at home. You can ask your pharmacist for advice on giving yourself injections.”
Below is a synopsis of how Dupixent is used.
What are the forms of Dupixent?
A single-dose prefilled pen and a single-dose prefilled syringe are the two forms of dupixent. The pen should only be used by people over the age of 12.
Your doctor will help determine which form is best for you.
What strengths does Dupixent come in?
The single-dose prefilled syringe is available in a number of strengths.
- 300 milligrams in 2 liters of solution.
- 200 tablets in 1.14 liters of solution.
- 100 tablets in 0.67 liters of solution.
The single-dose prefilled pen comes in two strengths: 300 mg in 2 mL of solution and 200 tablets in 1.14 liters of solution..
What are the typical dosages of Dupixent?
The information below describes dosages that are commonly used or recommended. But be sure to take the dosage your doctor prescribes for you. Your doctor will determine the best dosage to fit your needs.
For eczema and asthma, your starting dose of Dupixent will be higher than your maintenance (ongoing) dose. This higher starting dose is called a loading dose. You will usually receive a loading dose to help the drug reach a steady level in your body more quickly.
The drug is given every other week as a maintenance dose after the loading dose. There is no weekly option for Dupixent.
The table shows the recommended dosages for the conditions Dupixent is used to treat.
|Condition||Age||Loading dose||Maintenance dose|
|Asthma||6 to 11 years old||For children weighing 15 kilograms (kg)* to less than 30 kg, the dose is either:
• 100 mg every other week, or
|For children weighing 30 kg or more, the dose is 200 mg every other week|
|Asthma||12 years and older||400 mg (two 200-mg injections)||200 mg every other week|
|600 mg (two 300-mg injections)||300 mg every other week|
|Eczema||6 to 17 years old||For children weighing 15 kilograms (kg)* to less than 30 kg, the dose is 600 mg (two 300-mg injections)||300 mg every 4 weeks|
|For children weighing 30 kg to less than 60 kg, the dose is 400 mg (two 200-mg injections)||200 mg every other week|
|For children weighing 60 kg or more, the dose is 600 mg (two-300 mg injections)||300 mg every other week|
|Eczema||Adults||600 mg (2 Dupixent 300-mg injections)||300 mg every other week|
|Chronic rhinosinusitis with nasal polyps||Adults||300 mg every other week|
The weight is 2.2 pounds. 15 kilo is 33 kilo.
Dosage for asthma
Dupixent can be used in children and adults with moderate to severe asthma. The dosages for this condition are shown in the chart.
Asthma and eczema are both inflammatory conditions that have a strong connection. If you have both eczema and asthma, your doctor may start you on a higher dose of Dupixent. You may also have a higher dose if you’re taking oral corticosteroids (taken by mouth) to manage your asthma symptoms.
If you need a higher dose, you will start with a loading dose of 600. Your dose will be 300 every other week after that.
Dosage for eczema
Dupixent is used to treat moderate to severe eczema. The dosage chart can be used to learn more.
Dosage for chronic rhinosinusitis with nasal polyps
Dupixent is used to treat chronic rhinosinusitis with nasal polyps. For this condition, you won’t start with a loading dose. Instead, you’ll take the same dosage of Dupixent throughout your treatment. For details, see the dosage chart above.
Is Dupixent used long term?
Dupixent is used as a long-term treatment. If you and your doctor determine that Dupixent is safe and effective for you, you will likely use it for a long time.
What’s the dosage of Dupixent for children?
Dupixent is used to treat asthma in children. Children 6 to 11 years old have the same recommended dosage as children 12 years and older. The dosage is based on body weight for younger children.
“Dupixent is used to treat children with eczema. The child’s weight is the main factor in determining the dosage for the disease.”
The dosages for each use are shown in the chart above.
Depending on Your age. and the condition being treated, your doctor may need to adjust your Dupixent dose. A change in weight could lead to a change in dose.
If you have asthma or both, your doctor may prescribe a higher dosage of oral corticosteroids.
If you have questions about the Dupixent dosage, you should talk to your doctor.
“It is important to keep your injection appointments if you get your Dupixent dose at your doctor’s office. If you miss an appointment, call your doctor as soon as possible.”
If you give yourself injections at home, follow the advice below.
Every other week, the dose is injected.
If you miss a dose, you should get an injection as soon as possible. Continue with your regular schedule. If it has been longer than 7 days, then just skip the missed dose and continue with your regular schedule.
Every 4 weeks, the dose is injected.
If you miss a dose, you should get an injection as soon as possible. Continue your regular schedule. If it has been longer than 7 days, you should give yourself an injection and then start a new 4-week schedule.
If you have questions about your schedule, talk to your doctor or pharmacist. They can help you get back on track.
If you need help remembering to take your dose of Dupixent on time, try using a medication reminder. This can include setting an alarm, downloading a reminder app, or setting a timer on your phone. A kitchen timer can work, too.
The doctor may prescribe a different amount of Dupixent. These include:
- The type and severity of the condition you are treating.
- Your age.
- “You may have other conditions that affect Dupixent’s dosage.”
- For certain children.
The lowest dose your doctor will prescribe is the one that will help manage your condition. Ask your doctor or pharmacist if you have questions about your Dupixent dose. They can tell you more about the dose.
Dupixent is a prescription drug that comes as a prefilled syringe and prefilled pens. The drug is given as an injection under the skin of your abdomen (belly) or thigh. (When injecting into the abdomen, the drug should not be injected within 2 inches of the belly button.)
“You can get your Dupixent injections at your doctor’s office. In some cases, your doctor may show you how to give yourself injections at home. You and your doctor will decide how to receive Dupixent. This may depend on factors.”
- Your age.
- How often do you get Dupixent injections?
- Your insurance plan.
- Your comfort level with self-injection.
If you’re using Dupixent for asthma or eczema, the loading dose of two injections should be given in two different areas. After this, rotate the injection sites for your maintenance doses. You should not inject the drug into skin that is scarred, damaged, or irritated.
Before using Dupixent at home, you should remove the dose from the refrigerator. 45 minutes before your injection is the minimum time you should have. Remove the 200- and 100-mg dose from the refrigerator at least 30 minutes before your injection.
To learn more about how to use Dupixent, including step-by-step instructions for the prefilled syringe or pen and general injection tips, see the drug’s website. You can also ask your doctor or pharmacist for more information on how to self-inject Dupixent.
Do not use more than your doctor prescribes. Side effects can be serious if you use more than this.
What to do in case you use too much Dupixent
Call your doctor right away if you think you’ve used or received too much Dupixent. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.
“The drug manufacturer’s typical dosages are described in the sections above. If your doctor recommends Dupixent, they will prescribe the correct amount.”
Remember, you should not change your dosage of Dupixent without your doctor’s recommendation. Only take Dupixent exactly as prescribed. Talk with your doctor if you have questions or concerns about your current dosage.
Some questions you may want to ask your doctor.
- Will my Dupixent dosage change if I take other drugs?
- Will I have more side effects with a higher dose of Dupixent?
- Can I use the prefilled pen instead of the Dupixent prefilled syringe?
- “Will my Dupixent dosage change if it isn’t helping me?”
If you use Dupixent for asthma, sign up for Healthline’s allergies and asthma newsletter for treatment news and expert advice on managing your condition.
If my child weighs less than 15 kg (about 33 lb), what’s the Dupixent dose for eczema?
“Dupixent has not been studied in children who weigh less than 15 kilo. You can talk to your child’s doctor to see if it’s a good option for them. Your child’s doctor may suggest a lower dose of Dupixent or another drug to treat their condition.”
The Healthline Pharmacist TeamAnswers represent the opinions of our medical experts. All content is strictly informational and should not be considered medical advice.
Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.