If you have overactive bladder (OAB), you may be interested in treatment with Gemtesa. It’s a prescription drug used in adults to treat the following urinary symptoms caused by OAB:

  • urge incontinence (a sudden, intense urge to urinate that causes you to leak urine before you can get to a bathroom)
  • It is urgent to urinate right away.
  • frequency (needing to urinate often)

Gemtesa basics

Gemtesa comes as a tablet that you swallow. It contains the active ingredient vibegron. (An active ingredient is what makes a drug work.) Gemtesa belongs to a group of called beta-3 agonists.

Gemtesa isn’t available as a generic.

Gemtesa has side effects, dosage, price, and more.

Gemtesa may cause mild or serious side effects. Some of the more common side effects of Gemtesa are described in the lists below. All possible side effects are not included in these lists.

Side effects of a drug can depend on other factors.

  • Your age.
  • You have other health conditions.
  • You take other drugs.

“The doctor or pharmacist can tell you more about Gemtesa’s side effects. They can suggest ways to reduce side effects.”

Mild side effects

Here’s a list of some of the mild side effects that Gemtesa can cause. To learn about other mild side effects, talk with your doctor or pharmacist, or read Gemtesa’s prescribing information.

There are some mild side effects of Gemtesa that have been reported.

The side effects of many drugs can be gone in a few days. If they become intolerable, talk to your doctor or pharmacist.

The side effect is described in the section “Allergic reaction”.

Serious side effects

Gemtesa can have serious side effects, but they are not common. If you have serious side effects from Gemtesa, call your doctor. If you think you have a medical emergency, you should call the emergency number.

Gemtesa has been reported to have serious side effects.

The side effect is described in the section “Allergic reaction”.

Allergic reaction

Some people may have an allergic reaction to Gemtesa. Although allergic reactions weren’t reported in Gemtesa’s studies, these reactions have been reported since the drug was approved for use.

A mild allergic reaction can include some symptoms.

A more severe allergic reaction is not uncommon. A severe allergic reaction can cause swelling under your skin, usually in your lips, hands, or feet. They can include swelling of your mouth, throat, and tongue, which can cause trouble breathing.

If you have an allergic reaction to Gemtesa, call your doctor. If you think you have a medical emergency, call the emergency number.

Your doctor will recommend the dosage of Gemtesa that’s right for you. Below are commonly used dosages, but always take the dosage your doctor prescribes.

Form and strength (75 mg)

Gemtesa is tablets that you swallow. 75 milligrams is the strength they are available in.

Recommended dosage

Gemtesa will be taken once daily.

Questions about Gemtesa’s dosage

“There are many questions about Gemtesa’s dosage.”

  • What if I miss a dose of Gemtesa? If you miss a dose of Gemtesa, take it as soon as you remember. But if it’s almost time for your next dose, skip the missed dose and take your next dose as scheduled. You should not take more than one dose of Gemtesa at a time. Doing so could raise your risk of side effects.
  • Will I need to use Gemtesa long term? Yes. If you and your doctor agree that Gemtesa is safe and working well for you, you’ll likely use it long term.
  • How long does Gemtesa take to work? Gemtesa begins working after you take your first dose. But it may take a few weeks before your symptoms begin to ease. In studies, people whose symptoms improved with Gemtesa treatment had a decrease in overactive bladder symptoms within 2 to 12 weeks.

There are many factors that affect the cost of prescription drugs. What your insurance plan covers is one of the factors.

If you have questions about how to pay for your prescription, talk with your doctor or pharmacist. A program called Gemtesa Simple Savings Program may also be available for Gemtesa.

You can also check out this article to learn more about saving money on prescriptions.

Find out what the answers are to some questions.

How does Gemtesa compare with Myrbetriq and other alternatives?

If you’re considering treatment with Gemtesa, you may wonder how it compares with alternative treatments for overactive bladder (OAB), such as Myrbetriq or oxybutynin.

The table below has some important information about Gemtesa. Talk to your doctor or pharmacist about treatment options for OAB.

Drug Name Form Dose Generic available?
Gemtesa (vibegron) tablets that you swallow Once daily No
Myrbetriq (mirabegron) • extended-release tablets that you swallow • extended-release liquid suspension Once daily No
Ditropan XL (oxybutynin)* extended-release tablets that you swallow Once daily Yes
Vesicare (solifenacin) tablets that you swallow Once daily Yes

Other forms of roxbutynin are also available. Talk to your doctor or pharmacist about what you want to know.

Does Gemtesa cause weight gain?

No, Gemtesa isn’t known to cause weight gain. Weight changes weren’t reported in the drug’s studies.

Being overweight or obese can make OAB symptoms worse.

If you are concerned about your weight, talk to your doctor. They can suggest ways to manage your weight.

Gemtesa is used in adults who have the following urinary symptoms caused by overactive bladder (OAB):

  • urge incontinence (a sudden urge to urinate followed by losing control of your bladder)
  • It is urgent to urinate right away.
  • frequency (needing to urinate often)

OAB is a condition that causes a sudden urge to urinate, and it may cause incontinence (not being able to control urination). These symptoms are often unpredictable, which can affect your daily life.

The cause of OAB is not known. The bladder muscles contracting involuntarily are the cause of the symptoms. This sends signals to your brain that you need to urinate. It can cause your bladder to stop working.

Gemtesa works to relax bladder muscles by sending signals. This allows your bladder to fill before you need to urinate.

“Your doctor will explain how to take Gemtesa. They will explain how much to take and how often. Follow your doctor’s instructions.”

Taking Gemtesa

Gemtesa is tablets that you swallow. You should drink the water with the tablets.

Accessible medication containers and labels

“If you can’t read the label on your prescription, tell your doctor or pharmacist. Some pharmacies may provide medication labels.”

  • Have a large print.
  • Use the visual aids.
  • You can use a code on a phone to change the text into audio.

“If your current pharmacy doesn’t offer these options, your doctor or pharmacist may be able to recommend a new pharmacy.”

“If you have trouble opening your bottles, please let your doctor know. They may be able to put Gemtesa in a container. The drug’s container may be easier to open with the help of your pharmacist.”

Questions about taking Gemtesa

Some questions about taking Gemtesa are listed below.

  • Can Gemtesa be chewed, crushed, or split? Gemtesa tablets may be crushed and mixed with 1 tablespoon of applesauce. This mixture should be eaten right away with a full glass of water.
  • Should I take Gemtesa with food? You can take Gemtesa doses with or without food. But you should take each tablet with a full glass of water.
  • Is there a best time of day to take Gemtesa? No, there’s no best time of day to take Gemtesa. But you should take it around the same time each day. This helps keep a consistent level of the drug in your body.

Questions for your doctor

You may have questions about Gemtesa. Discuss your concerns with your doctor.

Here are a few tips that might help you.

  • Before your appointment, write down questions such as:
    • How will Gemtesa affect me?
  • Bring someone with you to your appointment to make you feel more comfortable.
  • “If you don’t understand something, ask your doctor to explain it.”

“Your doctor and other healthcare professionals are available to help you. They want you to get the best care possible. Don’t be afraid to ask questions or give feedback on your treatment”

Before you begin taking Gemtesa, it’s important to discuss certain considerations with your doctor. This includes any medical conditions you may have or You take other drugs..


Taking a medication with certain vaccines, foods, and other things can affect how the medication works. These effects are called interactions.

Before taking Gemtesa, you should tell your doctor about all your medication. You should also describe any vitamins, herbs, or supplements you use. Your doctor or pharmacist can tell you about any potential problems with Gemtesa.

The “Warnings” section contains information about drug-condition interactions.

Interactions with drugs or supplements

Gemtesa can interact with a drug. It is usually safe to take digoxin with Gemtesa, but your doctor may keep an eye on you.

Your doctor or pharmacist can give you more information.


If you have certain medical conditions, Gemtesa may not be right for you. These are drug-condition interactions. Other factors may affect whether Gemtesa is a good option.

Before you take Gemtesa, talk to your doctor about your health history. The factors to consider are listed below.

  • Severe kidney problems. In most cases, it should be safe for people with mild or moderate kidney problems (such as mild chronic kidney disease) to take Gemtesa. But if you have a severe kidney problem (such as end-stage kidney disease), your doctor will likely suggest a treatment other than Gemtesa. Gemtesa hasn’t been studied in people with severe kidney problems. To learn more, talk with your doctor.
  • Severe liver problems. People with mild or moderate liver problems are usually able to take Gemtesa. But the drug hasn’t been studied in people with severe liver problems. It’s not known if the drug is safe to use if you have severe liver problems. Alcoholic liver disease is an example of a liver problem that can be mild, moderate, or severe. Your doctor can tell you more about how severe your liver condition is. They can also discuss treatments that may be safer for you instead.
  • Trouble emptying your bladder or a weak urine stream. Gemtesa can cause urinary retention. If you already have trouble emptying your bladder, using Gemtesa could worsen your condition. Your doctor can determine whether it’s safe for you to take Gemtesa.
  • Allergic reaction. If you’ve had an allergic reaction to Gemtesa or any of its ingredients, your doctor will likely not prescribe Gemtesa. Ask them what other medications are better options for you.

Gemtesa and alcohol

There’s no known interaction between Gemtesa and alcohol. But alcohol and Gemtesa can cause some of the same side effects, including There is a throbbing head., There is a lot of diarrhea., and nausea. Combining the two could raise your risk of these side effects.

In addition, alcohol may worsen symptoms of overactive bladder. This is because alcohol can cause you to urinate more often, which may irritate your bladder.

If you drink alcohol, talk to your doctor about how much you can drink if you have a condition.

Pregnancy and breastfeeding

It is not known if Gemtesa is safe to use while pregnant or breastfeeding.

If you are pregnant, breastfeeding, or planning to become pregnant, you should talk to your doctor about Gemtesa.

Do not take more Gemtesa than your doctor tells you to. Taking more than this can cause serious side effects.

What to do in case you take too much Gemtesa

Call your doctor if you think you’ve taken too much Gemtesa. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource. But if you have severe symptoms, immediately call 911 or your local emergency number. Or go to the nearest emergency room.

If you’re interested in learning more about Gemtesa for treating overactive bladder (OAB) symptoms, talk with your doctor. Ask questions to help determine whether Gemtesa or another treatment is right for you. Some example questions to get you started include:

  • Do any of my medical conditions increase my risk of Gemtesa side effects?
  • If I frequently get urinary tract infectionss (UTIs), is it safe for me to take Gemtesa?
  • What should I do if my symptoms get worse while I take Gemtesa?

You may also be interested in learning more about medications for OAB and home remedies for OAB.

Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.