Glipizide, Oral Tablet

What is glipizide?

The drug is used for prescription purposes. It is an oral immediate-release and oral extended-release tablet.

Glipizide oral tablet is available as the brand-name drugs Glucotrol and Glucotrol XL. It’s also available as a generic drug. Generic drugs usually cost less. In some cases, they may not be available in every strength or form as the brand name versions.

Why it’s used

Glipizide is used to reduce The levels of blood sugar. in people with high blood sugar caused by type 2 diabetes.

How it works

Squinylureas are a class of drugs. A class of drugs is similar to one another. They have the same structure as other conditions and are often used to treat them.

The drug helps release the blood thinner from the body. The sugar is moved from your bloodstream to your cells. This lowers your The levels of blood sugar..

Glipizide side effects

“It can cause other side effects, but it doesn’t cause drowsiness.”

More common side effects

glipizide tablets can have more common side effects.

• low blood sugar.
• Stomach problems such as nausea, vomiting, and abdominal pain.
• weight gain
• dizziness
• There is a There is a skin rash..
• sweating
• fast heart rate

Serious side effects

If you have serious side effects, call your doctor. If you think you are having a medical emergency, call the emergency services. There are serious side effects and their symptoms.

• Low blood sugar. Symptoms can include:
  • It was It was intense hunger..
  • nervousness
  • Anxious.
  • sweating, chills, and clamminess
  • dizziness
  • fast heart rate
  • Lightheadedness.
  • It is too sleepy.
  • There is There is There is There is confusion….
  • blurred vision
  • There is a throbbing head.
  • Depression.
  • “Is it possible that I’m Irrisponsible?”
  • crying spells
  • nightmares and crying out in sleep
• Allergic reaction. Symptoms can include:
  • It is red, itchy, or dry.
  • There is a There is a skin rash..es
• Low blood cell or platelet counts. Symptoms can include:
  • infections
  • “It doesn’t stop as quickly as normal.”
• Low blood sodium levels. Symptoms can include:
  • nausea
  • vomiting
  • There is a throbbing head.
  • There is There is There is There is confusion….
  • fatigue
  • Weakness in the muscles.
  • Seizures.
  • A coma.
• Liver problems. Symptoms can include:
  • Your skin and eyes are pale.
  • There was stomach pain and swelling.
  • swelling in your legs and feet.
  • itchy skin
  • Dark urine.
  • The stool is tar-colored.
  • “It’s always feeling tired.”
  • nausea
  • vomiting
  • It was bruise easily.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare professional who knows your medical history.

Glipizide may interact with other medications

You can interact with other drugs and herbs with the glipizide oral tablet. Your doctor should be careful with your medications. If you are curious about how this drug might interact with other drugs, talk to your doctor or pharmacist.

You can reduce your chances of drug interactions by having all of your prescriptions filled at the same pharmacy. A pharmacist can check for drug interactions.

There are drugs that can cause interactions with glipizide.

Nonsteroidal anti-inflammatory drugs (NSAIDs)

These drugs can cause low blood sugar. when taken with glipizide. Examples of these drugs include:

• Ibuprofen.
• naproxen
• diclofenac is a drug.

Antifungal medications

These drugs can cause low blood sugar. when taken with glipizide. Examples of these drugs include:

• fluconazole
• Miconazole is a drug.
• It is a drug called ketoconazole.

Drugs that contain salicylate

These drugs can cause low blood sugar. when taken with glipizide. Examples of these drugs include:

• A drug called aspirin.
• salsalate

Drugs that contain a sulfonamide

These drugs can cause low blood sugar. when taken with glipizide. Examples of these drugs include:

• sulfacetamide is a drug.
• sulfadiazine is a drug.
• sulfamethoxazole/trimethoprim is a drug.

Blood thinner medication

Warfarin can cause low blood sugar. when taken with glipizide.

Depression drugs

Monoamine oxidase inhibitors (MAOIs) can cause low blood sugar. when taken with glipizide. Examples of these drugs include:

• Isocarboxazid is a person.
• phenelzine is a drug.

Selective serotonin reuptake inhibitors (SSRIs), such as fluoxetine, may also cause low blood sugar. when given with glipizide.

Heart and blood pressure medications (beta-blockers)

These drugs can cause low blood sugar. when taken with glipizide. Examples of these drugs include:

• Metoprolol.
• Atenolol

Hormones

glipizide can increase your The levels of blood sugar.. If you are taking these medications together, you should test your blood sugar. These drugs can be examples.

• danazol is a drug.
• Somatropin is a growth hormone.
• Glucagon is a drug.
• Birth control pills.
• The hormones estrogens and testosterone.

Drugs used to treat HIV

glipizide may increase your The levels of blood sugar.. If you are taking these medications together, you should test your blood sugar. These drugs can be examples.

• The name is Ampvirrena.
• Atazana is a drug.
• darunavir is a drug.
• fosThe name is Ampvirrena.

Adrenergic drugs

glipizide may increase your The levels of blood sugar.. If you are taking these medications together, you should test your blood sugar. These drugs can be examples.

• Albuterol is a drug.
• A drug called Epidermolysis bullosa.
• terbutaline

Diuretics (thiazide diuretics)

glipizide may increase your The levels of blood sugar.. If you are taking these medications together, you should test your blood sugar. These drugs can be examples.

• chlorothiazide
• chlorthalidone is a drug.
• The drug hydrochlorothiazide.

Corticosteroids

glipizide may increase your The levels of blood sugar.. If you are taking these medications together, you should test your blood sugar.

Anti-psychotic, anti-nausea, and anti-vomiting medications

glipizide may increase your The levels of blood sugar.. If you are taking these medications together, you should test your blood sugar. These drugs can be examples.

• chlorpromazine is a drug.
• promethazine is a drug.
• prochlorperazine is a drug.
• A drug.
• clozapine
• phenothiazines are used for drugs.
• Reserpine is a drug.

Heart and blood pressure medications

glipizide may increase your The levels of blood sugar.. If you are taking these medications together, you should test your blood sugar. These drugs can be examples.

• Amlodipine is a drug.
• It is called verapamil.
• Reserpine is a drug.
• Clenidine is a drug.

Antibiotics

Chloramphenicol can cause low blood sugar. when taken with glipizide.

Gout medication

Probenecid can cause low blood sugar. when taken with glipizide.

Thyroid medication

Levothyroxine may increase your The levels of blood sugar. when taken with glipizide. Be sure to test your blood sugar as directed by your doctor if you’re taking this drug with glipizide.

Medication to treat Seizures.

Phenytoin may increase your The levels of blood sugar. when taken with glipizide. Be sure to test your blood sugar as directed by your doctor if you’re taking this drug with glipizide.

Niacin

glipizide may increase your The levels of blood sugar.. If you are taking glipizide, you should test your blood sugar as directed by your doctor.

Phenylephrine

glipizide may increase your The levels of blood sugar.. If you are taking glipizide, you should test your blood sugar as directed by your doctor.

Drug to treat tuberculosis

Isoniazid may increase your The levels of blood sugar. when taken with glipizide. Be sure to test your blood sugar as directed by your doctor if you’re taking this drug with glipizide.

Cholesterol and type 2 diabetes medication

Colesevelam may increase your The levels of blood sugar. when taken with glipizide. If you need to take these drugs together, take glipizide at least 4 hours before you take colesevelam. Be sure to test your blood sugar as directed by your doctor if you’re taking this drug with glipizide.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare professional about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.

How to take glipizide

There are no possible dosages or forms included here. How often you take it will depend on your dose and form.

• Your age.
• The condition is being treated.
• How bad is your condition?
• You have other medical conditions.
• How do you react to the first dose?

Dosage for type 2 diabetes

Generic: Glipizide

• Form: oral immediate-release tablet
• Strengths: 5 mg, 10 mg

• Form: oral extended-release tablet
• Strengths: 2.5 mg, 5 mg, 10 mg

Brand: Glucotrol

• Form: oral immediate-release tablet
• Strengths: 5 mg, 10 mg

Brand: Glucotrol XL

• Form: oral extended-release tablet
• Strengths: 2.5 mg, 5 mg, 10 mg

The adult dosage is 18 to 64 years old.

• Extended-release tablets
  • 5mg taken by mouth once per day with breakfast.
  • 20 tablets per day is the maximum.
• Immediate-release tablets
  • 5mg taken by mouth twice per day, every 12 hours or 30 minutes before breakfast and dinner.
  • 40 percent of the daily maximum is 40 percent per day.

If you switch from immediate-release tablets to extended-release tablets, your dosage will be the same. If you take more than 20 tablets, your dosage will be 20.

The child dosage is 0 to 17 years old.

A safe and effective dose for children is not known.

The senior dosage is 65 years old.

You may be more sensitive to glipizide, which may increase your risk of low blood sugar.. Your doctor may start you on a lower dosage of 2.5 mg taken once per day.

Special considerations for the amount of medicine.

• If you have kidney or liver problems: Your doctor may start you on a lower dosage to avoid low blood sugar. levels.
• If you have malnutrition or adrenal or pituitary insufficiency: Your doctor may start you on a lower dosage to avoid low blood sugar. levels.
• If you’re taking other oral diabetes medications: If you’re adding glipizide extended-release tablets to other diabetes medications, your doctor may start you at a dosage of 5 mg per day. If you’re at increased risk of low blood sugar., your doctor may start you at a lower dosage.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. This information is not a substitute for medical advice. Always to speak with your doctor or pharmacist about dosages that are right for you.

Glipizide warnings

This drug has several warnings.

Fatal heart problems warning

If you are treated with diet alone or with diet plusinsulin, you are more likely to have fatal heart problems. Ask your doctor if glipizide is right for you.

Diabetic ketoacidosis warning

Don’t use this medication to treat diabetic ketoacidosis, a serious medical condition whose complications can include A coma.. This condition must be treated with insulin.

Low blood sugar warning

Glipizide can cause low blood sugar. (hypoglycemia). If you don’t treat low blood sugar., you can have a seizure, pass out, and possibly develop brain damage. Low blood sugar can even be fatal.

If you pass out because of a low sugar reaction or cannot swallow, someone will have to give an injection of Glucagon is a drug. to treat the low sugar reaction. You may need to go to the emergency room.

Allergy warning

A severe allergic reaction can be caused by glipizide. Symptoms may include:

• breathing problems
• “It’s swelling of your tongue or throat.”
• There are bees.
• There is a There is a skin rash..

If you have an allergic reaction, call your doctor or local poison control center right away. If your symptoms are severe, call 911 or your local emergency services or go to the nearest emergency room.

Don’t take this drug again if you’ve ever had an allergic reaction to it. Taking it again could be fatal.

Alcohol interaction warning

The drug can cause a disulfiram reaction when taken with alcohol. This reaction can have symptoms.

• There is a process of flushing.
• The heart rate went up.
• There is a throbbing head.
• Nausea and vomiting.
• There is There is There is There is confusion….
• The breath was very thin.
• It was faint.

Warnings for people with certain health conditions

For people with liver problems: If you have liver problems, you may not be able to clear this drug from your body as well as you should. Glipizide may build up in your body, which can cause lower The levels of blood sugar..

For people with kidney problems: If you have kidney problems, you may not be able to clear this drug from your body as well as you should. Glipizide may build up in your body, which can cause lower The levels of blood sugar..

For people who are sick, injured, or plan to have surgery: If you have a fever, trauma, infection, or surgery, you may not be able to control your The levels of blood sugar. with this drug. Your doctor may give you insulin temporarily instead.

For people with an enzyme deficiency: Don’t take glipizide if you have an enzyme deficiency of glucose-6-phosphate dehydrogenase (G6PD). You could get anemia.

For people with diabetic ketoacidosis: Don’t take glipizide if you have type 1 diabetes and diabetic ketoacidosis (with or without A coma.). Use insulin to treat this condition instead.

Warnings for other groups

For pregnant women: Talk with your doctor if you are pregnant or plan to become pregnant. Research in animals has shown adverse effects to the fetus when the mother takes the drug. There haven’t been enough studies in humans to be certain how the drug might affect the fetus. The drug should only be used if the potential benefit justifies the potential risk.

If you are pregnant, your doctor can help determine if this drug is safe for you to take.

For women who are breastfeeding: It isn’t known if glipizide passes through breast milk. If it does, it may cause serious effects in a breastfeeding child. You and your doctor may need to decide if you’ll take glipizide or breastfeed.

For seniors: Your body may process this drug more slowly. Your doctor may start you on a lowered dose to stop too much of the drug from building up in your body. Too much of the drug in your body can be toxic.

For children: This drug hasn’t been studied in children. It shouldn’t be used in people younger than 18 years.

Take as directed

“It is used for long-term treatment. It comes with serious risks if you don’t take it as prescribed.”

If you don’t take it at all or miss doses: If you don’t take glipizide at all or miss a dose, you may get high The levels of blood sugar.. Symptoms can include:

• Increased thirst.
• Increased urination.
• blurred vision
• It is extreme drowsiness.
• You are eating but feel very hungry.
• The cuts and injuries heal slowly.

If your The levels of blood sugar. stay high for too long, you may develop diabetes and develop other problems.

If you take too much: If you take too much glipizide, your low blood sugar. levels may get very low. Symptoms can include:

• It was It was intense hunger..
• nervousness
• Anxious.
• sweating, chills, or clamminess
• dizziness
• fast heart rate
• Lightheadedness.
• It is too sleepy.
• There is There is There is There is confusion….
• blurred vision
• There is a throbbing head.
• Mood changes.
• “Is it possible that I’m Irrisponsible?”

If you think you’ve taken too much of this drug, call your doctor or seek guidance from the American Association of Poison Control Centers at 1-800-222-1222 or through their online tool. But if your symptoms are severe, call 911 or go to the nearest emergency room right away.

What to do if you miss a dose: If you forget to take your dose, take it as soon as you remember before eating. If it’s just a few hours before the time for your next dose, only take one dose at that time. Never try to catch up by taking two doses at once. This could result in toxic side effects. Glipizide needs to be taken before eating or it will cause hypoglycemia.

How to tell if the drug is working: You may be able to tell if this drug is working if you have a decrease in your The levels of blood sugar. and your symptoms of diabetes get better. For instance, you may not be as thirsty or hungry, and you may not urinate as often.

Important considerations for taking glipizide

If your doctor prescribes glipizide, keep these considerations in mind.

General

• Take glipizide at the same time each day. Follow these guidelines for the type of tablet you’re taking.
  • Immediate-release tablets: Take these tablets 30 minutes before your first and last meal of the day. If you take these tablets with food, they may not work right away.
  • Extended-release tablets: Take with your first meal of the day.
• You can crush tablets. Do not crush extended-release tablets.

Storage

• Store glipizide in a room that is between 20 and 25C.
• “Don’t freeze glipizide.”
• Keep this drug away from the light.
• Keep your drugs away from wet areas.

Refills

“A prescription is not required. You don’t need a new prescription for this medication to be changed. Your doctor will write the number of refill you authorize.”

Travel

Traveling with your medication.

• Carry your medication with you. Never put it in a checked bag. It should be in your carry-on bag. You may need a letter stating that you need the medical supplies. This may be dependent on the airline and country you are in.
• “Don’t worry about the machines. They can not hurt this medication.”
• “You may need to show your pharmacy’s label to clearly identify the medication. You should keep the original prescription label with you.”

Self-management

Your doctor or pharmacist can show you how to use a blood sugar monitor. You will need to purchase more than the medication.

• A machine to test blood sugar at home.
• Alcohol samples.
• lancets to test your blood sugar.
• The strips are used to test blood sugar.
• A container for safe disposal of used lancets.

Clinical monitoring

Your doctor may do blood tests before and during treatment to make sure it is safe for you to take. These may include:

• The levels of blood sugar.
• The levels of the lysosomal hemoglobin. The test measures your blood sugar over the last few months.
• The function of the heart.
• The function of the kidneys.
• The function of the body.

Your doctor may do other tests to check for diabetes related problems.

• At least annually the eye exam is done.
• At least annually, the foot exam.
• At least annually, a dental exam.
• Nerve damage is tested.
• The levels of cholesterol.
• The heart rate and blood pressure are important.

Your diet

Follow the nutrition plan that your doctor, registered dietitian, or diabetes educator has recommended during your treatment with glipizide.

Are there any alternatives?

There are other drugs that can be used to treat your condition. Some may be more suitable for you. Talk to your doctor about alternatives.

Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up-to-date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or other healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.