If you have a relapsing form of multiple sclerosis (MS), your doctor might suggest Kesimpta as a treatment option. It’s a prescription drug used to treat the following conditions in adults:

Kesimpta comes as a liquid solution that’s given as an injection under your skin. It contains the active ingredient ofatumumab. (An active ingredient is what makes a drug work.)

Kesimpta belongs to a group of drugs called monoclonal antibodies, which are made from living cells. These drugs are also called biologics.

This article describes the dosage of Kesimpta, as well as its strength and how to take it. To learn more about Kesimpta, see this in-depth article.

Note: This chart highlights the basics of Kesimpta’s dosage. Be sure to read on for more detail.

Kesimpta forms Kesimpta strength Starting dosage Maintenance dosage
• prefilled syringe
• prefilled Sensoready pen
• 20 milligrams (mg) drug in 0.4 milliliter (mL) solution • inject one dose (20 mg) each week for 3 weeks
• skip the fourth week
• your first monthly dose will be at the start of the fifth week
• you’ll then inject one dose each month

Please keep in mind that this article covers Kesimpta’s standard dosage schedule, which is provided by the drug’s manufacturer. But always follow the dosing instructions your doctor prescribes.

Kesimpta has a dosage.

What are the forms of Kesimpta?

Kesimpta comes as a liquid solution that’s given as an injection under your skin. It comes in the following forms:

  • A single dose of prefilled syringe.
  • A pen with a single dose.

What strength does Kesimpta come in?

Kesimpta is a drug in a liquid solution.

What are the usual dosages of Kesimpta?

Your doctor will likely start you on the usual dosage of Kesimpta. They’ll ultimately prescribe the smallest dosage that provides the desired effect. The information below describes dosages that are commonly used or recommended. But be sure to take the dosage your doctor prescribes for you. They’ll determine the best dosage to fit your needs.

Dosage for There is a clinically isolated syndrome. (CIS) and certain kinds of multiple sclerosis (MS)

The recommended Kesimpta dose is the same for all of the conditions.

“You will probably get a 20-mg injection of Kesimpta once per week for 3 weeks. You won’t take a dose on the fourth week. A loading dose is a kind of schedule. You will start to respond faster to Kesimpta if you take more medication at the beginning of the schedule.”

You will begin your maintenance dose on the fifth week. You will probably get a 20-mg injection of Kesimpta once a month.

Is Kesimpta used long term?

Kesimpta is usually used for a long time. If you and your doctor agree that it is safe and effective for your condition, you will likely use it for a long time.

The amount of Kesimpta you are prescribed may be affected by a number of factors. These include:

  • The type and severity of the condition you are treating.
  • You are using the form of Kesimpta.
  • You have other health conditions.
  • You have received vaccines.

Kesimpta is given as an injection under your skin. You’ll get your first dose of Kesimpta with a healthcare professional present. They may give you the injection or instruct you on how to give it to yourself.

“Kesimpta is injected into the skin of your thighs or belly. If another person is giving you an injection, they can use your arm. Don’t inject skin that is bruised, broken, red, scaly, tender, or marked with stretch marks.”

The prescribing information has diagrams (starting on page 16 for the Sensoready pen, and page 22 for the prefilled syringe). The manufacturer’s website also has a helpful video on how to use the Sensoready pen. But always be sure to follow your doctor’s instructions.

For information on the expiration, storage, and disposal of Kesimpta, see this article.

Accessible drug containers and labels

“If you can’t read the prescription label on your medication, you should tell your doctor or pharmacist. Some pharmacies have labels for medication.”

  • Large print or use of blind.
  • You can use a code on a phone to change the text to sound.

“If your current pharmacy doesn’t offer accessibility features, your doctor or pharmacist may be able to recommend a new pharmacy.”

If you miss your Kesimpta dose, talk to your doctor. They will let you know what to do. If you miss your Kesimpta dose, you should inject it as soon as possible. Continue taking your dose every month. Let your doctor know that you missed the dose.

If you need help remembering to inject your dose of Kesimpta on time, try using a medication reminder. This can include setting an alarm or downloading a reminder app on your phone.

If you inject more Kesimpta than your doctor prescribes, you can have serious side effects.

What to do in case you use too much Kesimpta

Call your doctor right away if you think you’ve used too much Kesimpta. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource. But if you have severe symptoms, immediately call 911 (or your local emergency number) or go to the nearest emergency room.

Kesimpta has a dosage that is commonly asked questions.

Can I keep my Kesimpta doses in the fridge?

“You must keep Kesimpta in the refrigerator at 36F to 46F. Don’t freeze the medication. It is not exposed to light until you need it.”

How should I prepare for my first Kesimpta dose?

Before you get your first Kesimpta dose, your doctor will talk with you about which vaccines to get. Like some other biologic drugs, Kesimpta affects your immune system. Some vaccines won’t work as well if you take them during treatment with Kesimpta.

Your doctor will also test you for hepatitis B virus and certain immune system proteins in your blood before you begin treatment.

The drug manufacturer gives the usual dosage. If your doctor recommends Kesimpta, they will prescribe the right amount for you.

Remember, you shouldn’t change your dosage of Kesimpta without your doctor’s recommendation. Only take Kesimpta exactly as prescribed. Talk with your doctor if you have questions or concerns about your current dosage. Here are some examples of questions you may want to ask:

  • Will my Kesimpta dosage change if I take other drugs?
  • Do I need to skip a Kesimpta dose if I catch a cold?
  • Should I use the Kesimpta prefilled pen or the Sensoready pen?
  • Would a different dose of Kesimpta decrease my risk of side effects?

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Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.