Your doctor may prescribe Kineret for you if you have certain medical conditions. The drug keeret is used to treat diseases.

To learn more about these conditions and how Kineret is used, see the “What is the Kineret injection used for?” section below.

Kineret basics

Kineret contains the active ingredient anakinra, which is an interleukin-1 (IL-1) receptor antagonist medication. It comes as a solution in a prefilled syringe that you’ll inject under your skin.

Kineret is a biologic medication. A biologic is made from parts of living organisms. Anakinra is only available as the brand-name drug Kineret. It’s not available as a biosimilar drug. (Biosimilars are like generic drugs. But unlike generics, which are made for non-biologic drugs, biosimilars are made for biologic drugs).

Information on its uses, side effects, cost, and more can be found in this article.

The conditions it is approved to treat are listed.

RA is a chronic (long-lasting) immune system condition that causes inflammation (swelling and damage) of the joints. RA can also affect other organs and tissues in the body, such as the heart and lungs.

Kineret can help manage symptoms of moderate to severe RA. You must have tried a disease modifying antirheumatic drug before using Kineret.

NOMID is a rare disease that causes inflammation, and it’s usually diagnosed before a child is 6 months old. This condition causes There is a high degree of fever., There is a There is a skin rash.., joint swelling, and chronic meningitis.

Kineret is also used to treat The deficiency ofDIRA is related to the interleukin-1 receptor antagonist.. This is a rare, life-threatening disease that begins at birth. Symptoms of DIRA include There is a There is a skin rash.. with inflamed pustules (small, fluid-filled bumps), joint swelling, and bone lesions (areas of damaged bone).

DIRA is treated by blocking aProtein that is found in many different tissues and organs.

Kineret may also be used off-label for other conditions. (Off-label drug use is when an FDA-approved drug is prescribed for a purpose other than what it’s approved for.) For more information, talk with your doctor.

Mild or serious side effects may occur with Kineret. Some of the more common side effects of Kineret are described in the lists below. All possible side effects are not included in these lists.

Side effects of a drug can depend on other factors.

  • Your age.
  • You have other health conditions.
  • You take other drugs.

The doctor or pharmacist can tell you more about the side effects of Kineret. They can suggest ways to reduce side effects.

Mild side effects

Here’s a list of some of the mild side effects that Kineret can cause. To learn about other mild side effects, talk with your doctor or pharmacist, or read Kineret’s prescribing information.

Mild side effects of Kineret have been reported.

The side effects of many drugs can be gone in a few days. If they become intolerable, talk to your doctor or pharmacist.

Serious side effects

There are serious side effects from Kineret, but they are not common. If you have serious side effects from Kineret, you should call your doctor. If you think you have a medical emergency, you should call the emergency number.

There have been serious side effects of Kineret.

The side effect is described in the section “Allergic reaction”.

Allergic reaction

Some people may have an allergic reaction to Kineret.

A mild allergic reaction can include some symptoms.

A more severe allergic reaction is not uncommon. A severe allergic reaction can cause swelling under your skin, usually in your lips, hands, or feet. They can include swelling of your tongue, mouth, or throat, which can cause trouble breathing. People may have dizziness, fast heartbeat, or sweating.

It’s important to note that people using Kineret for The deficiency ofDIRA is related to the interleukin-1 receptor antagonist. have a higher risk of an allergic reaction to Kineret in the first few weeks of treatment. Doctors will closely monitor people using Kineret for DIRA and will stop treatment if needed.

If you have an allergic reaction to Kineret, call your doctor. If you think you have a medical emergency, call the emergency number.

Costs of prescription drugs can vary depending on many factors. These factors include what your insurance plan covers and which pharmacy you use. To find current prices for Kineret in your area, visit

If you have questions about how to pay for your prescription, talk with your doctor or pharmacist. A program called Kineret On Track may also be available for Kineret.

You can also check out this article to learn more about saving money on prescriptions.

Your doctor will recommend the dosage of Kineret that’s right for you. Below are commonly used dosages, but always take the dosage your doctor prescribes.


A single-use prefilled syringe is what keeret comes in. The liquid in the prefilled syringe has 100 milligrams of anakinra in it.

Recommended dosage

You’ll inject Kineret under your skin, typically once per day. The recommended injection sites for adults and children include:

  • The upper arm has an outer area.
  • The belly button is 2 inches around it.
  • The thighs are front of the body.
  • The buttocks have the upper and outer areas.

You should rotate your injection sites every day. This can help prevent Injection site reactions. such as pain, stinging, or swelling at the injection site.

You should take a dose at the same time every day. This helps to keep the drug in your body in a constant state.

Your doctor will explain how to inject the drug.

Questions about Kineret’s dosage

There are many questions about the dosage.

  • What if I miss a dose of Kineret? If you miss a dose of Kineret, talk with your doctor to find out when you should inject your next dose.
  • Will I need to use Kineret long term? Yes, Kineret is usually a long-term treatment. If you and your doctor determine the drug is safe and effective for you, you’ll likely use it long term.
  • How long does Kineret take to work? Some people using Kineret may see results within 3 months of starting treatment. If you have questions about what to expect from your Kineret treatment, talk with your doctor.

Find answers to questions about Kineret.

Is Kineret used for pericarditis?

Yes, Kineret is sometimes used to treat pericarditis (inflammation of tissue around the heart). The drug isn’t approved by the Food and Drug Administration (FDA) for this use, but it may be prescribed off-label for this condition. (Off-label drug use is when an FDA-approved drug is prescribed for a purpose other than what it’s approved for.)

If you are interested in using Kineret off label to treat pericarditis, you should talk to your doctor.

Is Kineret used to treat juvenile Rheumatoid arthritis is a disease.?

No, Kineret isn’t used to treat juvenile Rheumatoid arthritis is a disease. (JRA). Researchers haven’t determined whether Kineret is safe and effective for children with this condition.

A small study showed that Kineret can help control JRA symptoms when the drug is started early in the disease. But more studies are needed to understand the benefits and risks of prescribing Kineret for JRA.

Talk to your doctor if you have questions about treatment.

Is Kineret similar to the Rheumatoid arthritis is a disease. drugs Actemra (tocilizumab) and Kevzara (sarilumab)?

Kineret, Actemra, and Kevzara are all used to treat Rheumatoid arthritis is a disease. (RA). They belong to the same group of drugs and work in similar ways in your body. But Kineret targets a different protein in the body than Actemra and Kevzara.

Kineret, Actemra, and Kevzara all come in a solution that you inject under your skin. Actemra can also be given with an intravenous (IV) injection, which is an injection into your vein.

If you have questions about how Kineret compares to other drugs, talk to your doctor or pharmacist.

Your doctor will explain how to administer Kineret. They’ll also explain how much to use and how often. Be sure to follow your doctor’s instructions.

Injecting Kineret

Kineret comes as a solution in a prefilled syringe. You’ll inject Kineret under your skin. Your doctor will show you how to inject Kineret. You can inject it into the following areas:

  • The upper arm has an outer area.
  • The belly button has a 2-inch area.
  • The thighs are front of the body.
  • The buttocks have the upper and outer areas.

Accessible medication containers and labels

“If you can’t read the label on your prescription, tell your doctor or pharmacist. Some pharmacies may provide medication labels.”

  • Have a large print.
  • Use the visual aids.
  • You can use a code on a phone to change the text into audio.

“If your current pharmacy doesn’t offer these options, your doctor or pharmacist may be able to recommend a new pharmacy.”

“If you have trouble opening your bottles, please let your doctor know. They may be able to put it in a container. The drug’s container may be easier to open with the help of your pharmacist.”

Using Kineret with other drugs

Some people with Rheumatoid arthritis is a disease. may need to use Kineret with other drugs, such as methotrexate, to manage their condition. Methotrexate is another disease modifying antirheumatic drug (DMARD) used for arthritis.

Rheumatoid arthritis is a disease that gets worse over time. You may need to add or remove other medications to help manage your symptoms.

You might need to take Glucocorticoids with Kineret. If you need low doses of glucocorticoids, they can help.

Questions for your doctor

You may have questions about your treatment plan. Discuss your concerns with your doctor.

Here are a few tips that might help you.

  • Before your appointment, write down questions such as:
    • How will Kineret affect my body?
  • Bring someone with you to your appointment to make you feel more comfortable.
  • “If you don’t understand something, ask your doctor to explain it.”

“Your doctor and other healthcare professionals are available to help you. They want you to get the best care possible. Don’t be afraid to ask questions or give feedback on your treatment”

When considering Kineret treatment, it is important to discuss your health and any medical conditions you may have with your doctor.


Taking a medication with certain vaccines, foods, and other things can affect how the medication works. These effects are called interactions.

Before taking Kineret, you should tell your doctor about all your medications. You should also describe any vitamins, herbs, or supplements you use. Your doctor or pharmacist can tell you about any interactions these items may cause.

Interactions with drugs or supplements

There are several types of drugs that keeret can interact with. These drugs are used.

The list does not include all drugs that may interact with Kineret. Your doctor or pharmacist can tell you more about the interactions that may occur with use of Kineret.

Other interactions

“The keeret weakens your immune system. Doctors usually don’t recommend live vaccines during your treatment.”

Live vaccines contain a weakened form of a virus or germ they’re mean to protect against. People with weakened immune systems can get There is a serious infection.s with a live vaccine.

Examples of live vaccines include:

Talk to your doctor about any vaccines you may need. If you need a live vaccine, talk to your doctor.


If you have a medical condition that affects your health, keeret may not be right for you. Before you take Kineret, talk to your doctor about your health history. The factors to consider are listed below.

  • End-stage kidney disease or severe kidney disease. Your kidneys are responsible for removing Kineret from your blood. If you have end-stage kidney disease (ESKD) or severe kidney disease, your kidneys may not be effective at clearing Kineret from your body. This can raise your risk of side effects from the drug. You may still be able to use Kineret you have ESKD or severe kidney disease, but you’ll need a lower dosage. Before starting treatment, you may need a blood test to check how well your kidneys are working. Depending on the results, your doctor may adjust your dosage. If you have kidney disease, talk with your doctor about whether Kineret is right for you.
  • Allergic reaction. If you’ve had an allergic reaction to Kineret or any of its ingredients, your doctor will likely not prescribe Kineret. Ask them what other medications are better options for you.

Kineret and alcohol

It is safe to drink alcohol while using keeret.

If you drink alcohol, you should talk to your doctor about the amount that is safe for you to drink.

Pregnancy and breastfeeding

It’s not known whether Kineret is safe to use during pregnancy. But it’s important to note that uncontrolled Rheumatoid arthritis is a disease. is risky during pregnancy. If you’re pregnant or considering becoming pregnant, talk with your doctor about the risk and benefits of using Kineret.

It is not known if it is safe to use keeret while breastfeeding. Before using Kineret, talk with your doctor.

“Don’t take more than your doctor prescribes. Side effects can be serious if you inject more than this. Your doctor will determine the correct amount of Kineret.”

What to do in case you take too much Kineret

Call your doctor if you think you’ve injected too much Kineret. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource. But if you have severe symptoms, immediately call 911 or your local emergency number. Or go to the nearest emergency room.

Talk to your doctor if you have questions about taking the drug. Some questions you may want to ask.

If you’re taking Kineret for RA, this article about treatment options may be helpful. Also, consider signing up for Healthline’s RA newsletter to get helpful tips for managing your condition. You can also find support and advice from our Bezzy RA community.


If I need to stop using keeret, will I have withdrawal symptoms?



No, Kineret does not cause withdrawal symptoms. Withdrawal symptoms are side effects that can occur when you stop using a drug that you have become dependent on.

But once you stop using Kineret, the symptoms of your condition (such as inflammation) may return. In studies of Kineret, some people with NOMID is a disease of the newborn. had their symptoms return within about 5 days of stopping treatment.

If you want to end your treatment, you should talk to your doctor. They can discuss other options with you.

The Healthline Pharmacist TeamAnswers represent the opinions of our medical experts. All content is strictly informational and should not be considered medical advice.

Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.