Serious FDA warnings

The FDA has warned about the possible dangerous effects of this drug.

  • Tendon can break or be inflammation.
  • Nerve damage is the cause of peripheral neuropathy.
  • The central nervous system has effects.
  • Worsening of myasthenia gravis.
  • It is restricted use.

Tendon can break or be inflammation.. This drug is linked with an increased risk of tendon rupture and tendinitis (swelling of your tendons). This can happen at any age. The risk is higher if you’re over 60 years of age or are taking corticosteroid drugs. It’s also higher if you’ve had a kidney, heart, or lung transplant.

Nerve damage is the cause of peripheral neuropathy.. This drug may cause peripheral neuropathy. This condition causes damage to the nerves in your arms, hands, legs, or feet, which lead to changes in sensation. This damage may be permanent. Stop taking this drug and call your doctor right away if you have any signs of peripheral neuropathy. Symptoms include It is a It is a pain.., burning, tingling, There is numbness., and weakness.

The central nervous system has effects.. This drug raises your risk of central nervous system (CNS) effects. These can include convulsions, psychosis, and increased pressure inside your head. This drug can also cause tremors, agitation, anxiety, There is confusion., delirium, and hallucinations. In addition, it can cause paranoia, Depression., nightmares, and “It’s difficult to sleep.”. Rarely, it can cause suicidal thoughts or acts. Be sure to tell your doctor if you’re at increased risk of Seizures..

Worsening of myasthenia gravis.. This drug may make your muscle weakness worse if you have myasthenia gravis. You shouldn’t take this drug if you have a history of this condition.

It is restricted use.. This drug can cause serious side effects. As a result, it should only be used to treat certain conditions if no other treatment options exist. These conditions are uncomplicated urinary tract infection, acute bacterial exacerbation of chronic bronchitis, and acute bacterial sinusitis.

  1. Levofloxacin oral tablet is available as a generic drug and under the brand name Levaquin.
  2. Levofloxacin can be used as an oral solution and eye drops. It is only given by a healthcare professional.
  3. Levofloxacin is used to treat infections.

Levofloxacin is a prescription drug that comes in three forms. It is only given by a healthcare provider.

Levofloxacin is a generic drug and is sold under the brand name Levaquin. Generic drugs are usually cheaper than brand-name drugs.

Why it’s used

Levofloxacin is used to treat infections in adults. These infections include:

  • Pneumonia.
  • There is a sinus infection.
  • The chronic bronchitis is getting worse.
  • There are skin infections.
  • There is a chronic disease of the prostrate.
  • There are infections in the urinary tract.
  • pyelonephritis (kidney infection)
  • inhalational anthrax
  • The plague.

Levofloxacin may be used in combination therapy. You may need to take it with other drugs.

How it works

Levofloxacin belongs to a class of drugs called fluoroquinolone antibiotics. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.

Levofloxacin works by killing the infections that are caused by the bacteria. You should only use this drug if you have a serious illness.

Levofloxacin can make you feel unwell. You should not do things that require coordination or alert until you know how it affects you.

Levofloxacin can cause side effects. The following list contains some of the side effects that may occur when taking levofloxacin. All possible side effects are not included in this list.

Talk to your doctor or pharmacist if you have questions about the possible side effects of levofloxacin or how to deal with a troubling side effect.

More common side effects

There are some common side effects of levofloxacin.

  • nausea
  • There is a throbbing head.
  • There is a lot of diarrhea.
  • insomnia (“It’s difficult to sleep.”)
  • It is a problem of the colon.
  • dizziness

The effects may go away in a few days or weeks. If they are more severe, you should talk to your doctor or pharmacist.

Serious side effects

If you have serious side effects, call your doctor. If you think you are having a medical emergency, call the emergency room. There are serious side effects and their symptoms.

  • Allergic reaction. Symptoms can include:
    • There are bees.
    • Breathing problems or swallowing problems.
    • Your lips are swollen, your tongue is swollen.
    • throat tightness
    • fast heart rate
    • It was faint.
    • There is a skin rash.
  • The central nervous system has effects.. Symptoms can include:
    • Seizures.
    • hallucinations (hearing voices, seeing things, or sensing things that aren’t there)
    • It is restless.
    • anxiety
    • tremors (uncontrollable rhythmic movement in one part of your body)
    • feeling anxious
    • There is confusion.
    • Depression.
    • “It’s difficult to sleep.”
    • nightmares
    • Lightheadedness.
    • paranoia (feeling suspicious)
    • suicidal thoughts or actions
    • a There is a throbbing head. that won’t go away, with or without blurred vision
  • Tendon damage, including tendinitis (inflammation of the tendon) and tendon rupture (tear in the tendon). Symptoms can occur in joints such as the knee or elbow and include:
    • It is a It is a pain..
    • reduced ability to move
  • Peripheral neuropathy (nerve damage in your hands, feet, arms, or legs). Symptoms typically occur in the hands and feet and can include:
    • It is a It is a pain..
    • There is numbness.
    • weakness
  • Joint and muscle It is a It is a pain..
  • Liver damage, which can be fatal. Symptoms can include:
    • The appetite has been lost.
    • nausea
    • vomiting
    • There is a high degree of fever.
    • weakness
    • It is a problem of tiredness.
    • It was itching.
    • Your skin and eyes are pale.
    • Light colored bowel movements.
    • It is a It is a pain.. in your abdomen
    • dark-colored urine
  • Severe There is a lot of diarrhea. caused by the bacteria Clostridium difficile. Symptoms can include:
    • watery and bloody stools.
    • stomach ache.
    • There is a high degree of fever.
  • Heart rhythm problems, such as prolongation of the QT interval. Symptoms can include:
    • irregular heart rhythm.
    • loss of consciousness
  • Increased sensitivity to the sun. Sunburn of the skin can be symptoms.

Levofloxacin can interact with other drugs. Different interactions can have different effects. Some drugs can cause side effects that are different from the ones that work.

There are medications that can interact with levofloxacin. The drugs on this list are not related to levofloxacin.

Before taking levofloxacin, you should tell your doctor and pharmacy about all your drugs. Tell them about the vitamins, herbs, and supplements you use. Sharing this information can help you avoid potential interactions.

Ask your doctor or pharmacist if you have questions about drug interactions.

Drugs that increase the risk of side effects

Taking levofloxacin with certain drugs can cause side effects. These drugs can be examples.

  • Insulin and certain oral diabetes drugs, such as nateglinide, pioglitazone, repaglinide, and rosiglitazone. You may have a significant decrease or increase in your blood sugar levels. You may need to monitor your blood sugar levels closely while taking these drugs together.
  • Warfarin. You may have an increase in bleeding. Your doctor will monitor you closely if you take these drugs together.
  • Nonsteroidal anti-inflammatory drugs (NSAIDs). Drugs such as ibuprofen and naproxen may increase the risk of central nervous system stimulation and Seizures.. Tell your doctor if you have a history of Seizures. before you start taking levofloxacin.
  • Theophylline. You may have symptoms such as Seizures., low blood pressure, and irregular heartbeat due to increased levels of theophylline in your blood. Your doctor will monitor you closely if you take these drugs together.

Drugs that can make levofloxacin less effective

“These drugs can make levofloxacin less effective. It won’t work to treat your condition. These drugs can be examples.”

  • Sucralfate, didanosine, multivitamins, antacids, or other drugs or supplements that contain magnesium, aluminum, iron, or zinc may reduce levels of levofloxacin and stop it from working correctly. Take levofloxacin either 2 hours before or 2 hours after taking these drugs or supplements.

The levofloxacin dosage will be determined by a number of factors. These include:

  • The type and severity of the condition you are treating.
  • Your age.
  • Your weight.
  • You may have other medical conditions.

Your doctor will usually start you on a low dose and adjust it over time to reach the right amount for you. They will prescribe the smallest dose that will provide the desired effect.

The following information describes dosages that are commonly used or recommended. However, be sure to take the dosage your doctor prescribes for you. Your doctor will determine the best dosage to suit your needs.

Forms and strengths

Generic: Levofloxacin

  • Form: oral tablet
  • Strengths: 250 mg, 500 mg, 750 mg

Dosage for Pneumonia.

The adult dosage is 18 to 64 years old.

  • hospital-acquired Pneumonia.: 750 mg taken every 24 hours for 7 to 14 days.
  • community-acquired Pneumonia.: 750 mg taken every 24 hours for 5 days. Your dosage will depend on the type of bacteria causing your infection.

The child dosage is 0 to 17 years old.

This drug should not be used in children younger than 17 years old.

Older adult dosage.

Older adults may not be able to use their kidneys as effectively as they used to. Your body can process drugs more slowly if this is the case. More drugs stay in your body for a longer time. This increases the risk of side effects.

Your doctor may start you with a lower dose or a different schedule. This can help keep the drug out of your body.

Dosage for acute bacterial sinusitis

The adult dosage is 18 to 64 years old.

500 and 750 were taken every 24 hours for 10 and 5 days. The amount of your dose will be dependent on the cause of the infection.

The child dosage is 0 to 17 years old.

This drug should not be used in children younger than 17 years old.

Older adult dosage.

Older adults may not be able to use their kidneys as effectively as they used to. Your body can process drugs more slowly if this is the case. More drugs stay in your body for a longer time. This increases the risk of side effects.

Your doctor may start you with a lower dose or a different schedule. This can help keep the drug out of your body.

Dosage for acute bacterial exacerbation of chronic bronchitis

The adult dosage is 18 to 64 years old.

500mg taken every 24 hours.

The child dosage is 0 to 17 years old.

This drug should not be used in children younger than 17 years old.

Older adult dosage.

Older adults may not be able to use their kidneys as effectively as they used to. Your body can process drugs more slowly if this is the case. More drugs stay in your body for a longer time. This increases the risk of side effects.

Your doctor may start you with a lower dose or a different schedule. This can help keep the drug out of your body.

Dosage for skin and skin structure infections

The adult dosage is 18 to 64 years old.

  • Complicated skin and skin structure infections (SSSI): 750 mg taken every 24 hours for 7 to 14 days.
  • Uncomplicated SSTI: 500 mg taken every 24 hours for 7 to 10 days.

The child dosage is 0 to 17 years old.

This drug should not be used in children younger than 17 years old.

Older adult dosage.

Older adults may not be able to use their kidneys as effectively as they used to. Your body can process drugs more slowly if this is the case. More drugs stay in your body for a longer time. This increases the risk of side effects.

Your doctor may start you with a lower dose or a different schedule. This can help keep the drug out of your body.

Dosage for chronic bacterial prostatitis

The adult dosage is 18 to 64 years old.

500mg taken every 24 hours.

The child dosage is 0 to 17 years old.

This drug should not be used in children younger than 17 years old.

Older adult dosage.

Older adults may not be able to use their kidneys as effectively as they used to. Your body can process drugs more slowly if this is the case. More drugs stay in your body for a longer time. This increases the risk of side effects.

Your doctor may start you with a lower dose or a different schedule. This can help keep the drug out of your body.

Dosage for There are infections in the urinary tract.

The adult dosage is 18 to 64 years old.

  • Complicated urinary tract infection or acute pyelonephritis: 750 mg taken every 24 hours for 5 days. Your dose will depend on the type of bacteria causing the infection.
  • Uncomplicated urinary tract infection: 250 mg taken every 24 hours for 3 days.

The child dosage is 0 to 17 years old.

This drug should not be used in children younger than 17 years old.

Older adult dosage.

Older adults may not be able to use their kidneys as effectively as they used to. Your body can process drugs more slowly if this is the case. More drugs stay in your body for a longer time. This increases the risk of side effects.

Your doctor may start you with a lower dose or a different schedule. This can help keep the drug out of your body.

Dosage for inhalational anthrax, post-exposure

The adult dosage is 18 to 64 years old.

500mg taken every 24 hours.

The child dosage is 6 months to 17 years old.

  • Inhalational anthrax (post-exposure) in children who weigh 110 lbs (50 kg) or greater: 500mg taken every 24 hours.
  • Inhalational anthrax (post-exposure) in children who weigh 66 lbs (30 kg) to < 110 lbs (50 kg): 250 mg taken every 12 hours for 60 days.

The child dosage is 0–5 months.

“The drug hasn’t been studied in children younger than 6 months. It should not be used in this age group.”

Older adult dosage.

Older adults may not be able to use their kidneys as effectively as they used to. Your body can process drugs more slowly if this is the case. More drugs stay in your body for a longer time. This increases the risk of side effects.

Your doctor may start you with a lower dose or a different schedule. This can help keep the drug out of your body.

Dosage for The plague.

The adult dosage is 18 to 64 years old.

500mg taken every 24 hours.

The child dosage is 6 months to 17 years old.

  • Plague in children who weigh 110 lbs (50 kg) or greater: 500mg taken every 24 hours.
  • Plague in children who weigh 66 lbs (30 kg) to < 110 lbs (50 kg): 250 mg taken every 12 hours for 10 to 14 days.

The child dosage is 0–5 months.

“The drug hasn’t been studied in children younger than 6 months. It should not be used in this age group.”

Older adult dosage.

Older adults may not be able to use their kidneys as effectively as they used to. Your body can process drugs more slowly if this is the case. More drugs stay in your body for a longer time. This increases the risk of side effects.

Your doctor may start you with a lower dose or a different schedule. This can help keep the drug out of your body.

Special considerations

If you have a problem with your kidneys, your doctor will adjust your dose and how often you take it. The amount of damage to your kidneys will be the basis for your dosage.

FDA warnings

  • The drug has warnings. The FDA has the most serious warnings. It informs doctors and patients about drug effects.
  • Tendon can break or be inflammation. warning. This drug is linked with an increased risk of tendon rupture and tendinitis (swelling of your tendons). This can happen at any age. This risk is higher if you’re over 60 years old or are taking corticosteroid drugs. It’s also higher if you’ve had a kidney, heart, or lung transplant.
  • Nerve damage is the cause of peripheral neuropathy.. This drug may cause peripheral neuropathy. This condition causes damage to the nerves in your arms, hands, legs, or feet, which lead to changes in sensation. This damage may be permanent. Stop taking this drug and call your doctor right away if you have any signs of peripheral neuropathy. Symptoms include It is a It is a pain.., burning, tingling, There is numbness., and weakness.
  • The central nervous system has effects.. This drug raises your risk of central nervous system (CNS) effects. These can include convulsions, psychosis, and increased pressure inside your head. This drug can also cause tremors, agitation, anxiety, There is confusion., delirium, and hallucinations. In addition, it can cause paranoia, Depression., nightmares, and “It’s difficult to sleep.”. Rarely, it can cause suicidal thoughts or acts. Be sure to tell your doctor if you’re at increased risk of Seizures..
  • Worsening of myasthenia gravis. warning. This drug may make your muscle weakness worse if you have myasthenia gravis. You shouldn’t take this drug if you have a history of this condition.
  • It is restricted use.. This drug can cause serious side effects. As a result, it should only be used to treat certain conditions if no other treatment options exist. These conditions are uncomplicated urinary tract infection, acute bacterial exacerbation of chronic bronchitis, and acute bacterial sinusitis.

Liver damage warning

This drug can cause damage to the body. If you have any signs of a problem with the liver, call your doctor.

Symptoms can include nausea or vomiting, stomach It is a It is a pain.., There is a high degree of fever., weakness, and abdominal It is a It is a pain.. or tenderness. They can also include It was itching., unusual It is a problem of tiredness., The appetite has been lost., Light colored bowel movements., dark-colored urine, and yellowing of your skin or the whites of your eyes.

Heart rhythm changes warning

If you have a fast heartbeat or faint, tell your doctor. This drug may cause a heart problem. An abnormal heartbeat can be caused by this serious condition.

If you have a family history of QT prolongation, have low blood potassium, or take drugs to control your heart rhythm, you may be at higher risk.

Suicidal thoughts and behaviors warning

This drug can cause suicidal thoughts or behaviors. Your risk is greater if you have a history of Depression.. Call your doctor right away if you have thoughts of harming yourself while taking this drug.

Allergy warning

Levofloxacin can cause a severe allergic reaction even after only one dose. Symptoms can include:

  • There are bees.
  • Breathing problems or swallowing problems.
  • Your lips are swollen, your tongue is swollen.
  • throat tightness
  • fast heart rate
  • It was faint.
  • There is a skin rash.

If you have an allergic reaction, call your doctor or poison control center. If you have a serious illness, you can call the emergency room.

Don’t take this drug again if you’ve ever had an allergic reaction to it. Taking it again could be fatal (cause death).

Warnings for people with certain conditions

For people with diabetes: People who take levofloxacin with diabetes drugs or insulin can develop low blood sugar (hypoglycemia) or high blood sugar (hyperglycemia). Severe problems, such as coma and death, have been reported as a result of hypoglycemia.

Your doctor recommends that you test your blood sugar frequently. If you have low blood sugar levels while taking this drug, stop and call your doctor. Your doctor may need to change your antibiotic.

For people with kidney damage: Your doctor will adjust your dosage and how often you take levofloxacin, based on how much your kidneys are damaged.

For people with myasthenia gravis: This drug may make your muscle weakness worse. You should not take this drug if you have a history of this condition.

Warnings for other groups

For pregnant people: Levofloxacin is a category C pregnancy drug. That means two things:

  1. The offspring of mothers who take drugs have shown adverse effects.
  2. There are not enough studies done to know how the drug might affect the fetus.

“If you are pregnant or planning to become pregnant, talk to your doctor. The drug should only be used if it is justified. If your infection doesn’t get better within a week, you should call your doctor.”

For women who are nursing: Levofloxacin passes into breast milk and may cause side effects in a child who is being nursed.

If you nurse your child, talk to your doctor. You have to decide if you should stop nursing or take this medication.

For older adults: The kidneys of older adults may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, more of a drug stays in your body for a longer time. This raises your risk of side effects.

For children.

  • Age range: This drug hasn’t been studied in children younger than 6 months for certain conditions.
  • Increased risk of muscle and bone problems: This drug can cause problems in children. These problems include joint It is a It is a pain.., arthritis, and tendon damage.

“Levofloxacin is used for short-term treatment. It comes with risks if you don’t take it as prescribed.”

If you stop taking the drug or don’t take it at all: Your infection won’t get better and may get worse. Even if you feel better, don’t stop taking the drug.

If you miss doses or don’t take the drug on schedule: Your medication may not work as well or may stop working completely. For this drug to work well, a certain amount needs to be in your body at all times.

If you take too much: You could have dangerous levels of the drug in your body. Symptoms of an overdose can include:

  • dizziness
  • It is not good to be drowsiness.
  • Experiencing confusion
  • slurred speech
  • nausea
  • vomiting

If you think you’ve taken too much of this drug, call your doctor or seek guidance from the American Association of Poison Control Centers at 800-222-1222 or through their online tool. But if your symptoms are severe, call 911 or go to the nearest emergency room right away.

What to do if you miss a dose

“Take your dose as soon as you remember. If you remember a few hours before your next dose, take only one. Don’t try to catch up by taking two doses at once. This could cause serious injuries.”

How to tell if the drug is working: Your symptoms should get better, and your infection should go away.

Levofloxacin is primarily excreted through urine. The time it takes for about 50 percent of the initial levofloxacin dose to be removed from the body is 6 to 8 hours.

If your doctor prescribes levofloxacin oral tablet, keep these considerations in mind.

General

  • You can take this drug with or without food. It may help to take it with food.
  • You can crush the device.

Storage

  • Store this drug in the 70s to 80s.
  • Do not store this medication in damp areas.

Refills

“A prescription is not required. You don’t need a new prescription for this medication to be changed. Your doctor will write the number of refill you authorize.”

Travel

Traveling with your medication.

  • Carry your medication with you.
  • Never put it in a checked bag.
  • It should be in your carry-on bag.
  • “Don’t worry about the machines. They can not hurt your medication.”
  • You may need to show the pharmacy label to the airport staff. You should always carry the original box.
  • Do not put this medication in your car or leave it in the car. It is very hot or very cold when this is happening.

Clinical monitoring

Your doctor may perform tests on you while you take this drug.

  • Liver function tests: Your doctor may do blood tests to check how well your liver is working. If your liver isn’t working well, your doctor may have you stop taking this drug.
  • Kidney function tests: Your doctor may do blood tests to check how well your kidneys are working. If your kidneys aren’t working well, your doctor may give you less of the drug.
  • White blood cell count: A white blood cell count measures the number of cells in your body that fight infection. An increased count is a sign of infection.

Sun sensitivity

The drug can make your skin more sensitive to the sun. This increases the risk of sunburn. If you can, stay out of the sun. Wear protective clothing and sunscreen if you have to be outside.

Levofloxacin and alcohol

Alcohol consumption may reduce the effectiveness of certain antibiotics, but according to a 2020 review, moderate alcohol consumption does not seem to have an adverse effect on Levofloxacin. As always, talk with your doctor about what they believe is the best course of action when it comes to drinking and antibiotics.

Insurance

Insurance companies require prior authorization for this drug. Your insurance company will pay for the prescription if your doctor gets approval from them.

There are other drugs that can be used to treat your condition. Some may be better suited for you. Discuss with your doctor if there are other drug options that may work for you.

Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.