Three conditions are grouped together. They share some of the same symptoms and causes.

Doctors have noticed a relationship between these conditions for years, and recent studies have supported that observation.

What are gout, psoriasis, and psoriatic arthritis?

Gout is a common form of inflammatory arthritis. It causes intense pain, swelling, and sometimes structural changes in tissues around joints, due to a buildup of uric acid crystals. It commonly affects the big toe but can affect other joints as well.

Gout affects about 4% of the U.S. population, or about 9.2 million people. It’s more common in men, older adults, and the Black community.

Psoriasis is an autoimmune condition that causes your skin cells to turn over too quickly, leading to silvery, itchy patches of skin that are sometimes ringed with redness. It happens when your immune system attacks your own body.

Psoriasis affects more than 7.55 million people in the United States, according to 2020 U.S. census data. The data shows that it’s most common in white people and occurs at roughly the same rate in men and women.

PsA is an autoimmune condition that includes the itchy, scaly skin patches of psoriasis with the stiff, sore, and inflamed joints of arthritis. PsA affects between 2% and 4% of adults.

A 2015 study found that while PsA was more common in white people, it tended to be more severe in Black people. More research is needed in this area, though.

Both psoriasis and PsA are related to your body’s immune response. Between 20% and 30%of people with psoriasis also have PsA.

“The severity ofPsoriasis doesn’t determine whether you will develop PsA, and having one does not mean you will have the other. PsA can be had without having Psoriasis.”

How does that relate to gout?

Doctors have noticed for decades that there’s a connection between psoriasis, PsA, and gout, according to the Arthritis Foundation. Studies in the last few years have backed this up.

For instance, a 2015 study that examined nearly 100,000 men and women found that both conditions were positively correlated with gout. The study had its limitations, however, as it was conducted solely among healthcare professionals, 96% to 98% of whom were white.

A 2022 study also found a link between psoriasis and gout, but it was a nationwide study of only Taiwanese people. More research is needed in other populations.

The link between psoriatic disease and gout seems to be uric acid. A buildup of it in your body tissues and joints can lead to gout. A diet of foods rich in purines can cause higher uric acid buildup.

Psoriasis and PsA, which produce high levels of uric acid (called hyperuricemia) as a byproduct of high cell turnover and inflammation, may also lead to gout.

People with psoriasis also have higher levels of certain cytokines that play a role in the development of gout. Cytokines are molecules that promote inflammation and can overstimulate the activity of other immune cells, called a cytokine storm.

Gout was thought to be caused by a diet rich in alcohol, red meat and other foods. While diet plays a part, research shows that genetics, age, gender, and even the amount of calories eaten may have more to do with it.

Some gout risk factors are:

Gout in the Black community

A 2016 review of studies found that gout was more common in the Black population, mainly due to a higher prevalence of other conditions including There is a disease called diabetes., chronic kidney disease, “It’s obese.”, and hypertension.

A study found that many people with gout, especially Black people, were less likely to be treated by physicians in accordance with recognized standards.

The study found that PsA was more severe in black people than in white people.

If you have PsA, doctors can help you avoid gout.

If you have symptoms of psoriasis, PsA, or gout, it’s important to see a healthcare professional.

All three conditions can damage your joints and can be left unaddressed. gout can be extremely painful and can lead to joint damage.

There are a lot of questions about gout and its relationship with psoriatic disease.

Can psoriasis cause gout?

It is not clear if sphygmomany causes gout, but research shows an association. There is more research that is needed.

Can psoriatic arthritis cause gout?

PsA is associated with gout. PsA contributes to higher uric acid levels and certain inflammatory molecules. It is not clear if it causes gout.

What’s the difference between gout and psoriatic arthritis?

They have some common symptoms, such as joint pain, but they also have different symptoms.

PsA symptoms include:

  • The symptoms of sychosis.
  • nail changes that are crumbling
  • It is less common in gout.
  • The swelling of several fingers and toes.
  • Eye inflammation.
  • There is pain in the tendons.

Gout symptoms include:

  • Flare-ups in between periods of no symptoms.
  • The big toe is especially affected by the pain.
  • There are bumps and lump around joints.

Psoriasis, PsA, and gout have their own symptoms and a strong relationship to each other.

You are more likely to have PsA if you have Psoriasis. Both of those conditions can cause gout, and the inflammation that can occur from it.

If you have PsA, it is important to let your healthcare team know so they can monitor your blood or joint fluid for markers indicating the development of gout.

If left unaddressed, all three conditions can have serious health effects. It is important to speak with a doctor if you have any symptoms.