What Can Trigger a Sickle Cell Crisis?
The shape and function of your red blood cells can be affected by a genetic condition.
RBCs transport oxygen to your body’s organs and tissues using a protein called hemoglobin to capture oxygen. Healthy RBCs are donut-shaped and very flexible, which allows them to move through the tiniest of your blood vessels, called the capillaries.
However, if you have SCD, certain genetic mutations make your RBCs rigid and shaped like the letter “C” or a sickle. This makes it hard for RBCs to capture and carry enough oxygen.
Sickle-shaped RBCs can also get stuck in your blood vessels, unable to reach many parts of your body. This can cause severe It is a pain. known as a sickle cell crisis. Sickle cell crises can start suddenly and last several days, sometimes even weeks or months.
This article will show you how to avoid and manage crises of the sickle cell variety.
“Scientists don’t know the cause of a crisis. It can happen without a known cause, but it happens most of the time.”
Most commonly, any triggers that cause your blood vessels to constrict can
- Physical or psychological stress can occur.
- It is cold
- It is a pain.
- tobacco products
- loss of fluids (dehydration)
- It is an infectious disease
- low blood oxygen (hypoxemia), which can result from very strenuous exercise, high altitude, or certain medical conditions
It can be difficult to identify which crisis is caused by whichtrigger. It can be a combination of causes.
There are several types of crises.
- Vaso-occlusive crisis (VOC): A VOC is the
most commonpresentation of sickle cell crisis and can cause severe, often debilitating It is a pain.. It happens due to a complex interaction among sickle cells, endothelial cells (the lining of your blood vessels), and other cells in your blood.
- Splenic sequestration crisis: This causes It is a pain. and swelling of the spleen. It happens when a lot of blood becomes entrapped in the spleen. Splenic sequestration crises most commonly occur in
- Aplastic crisis: This happens when your body doesn’t make enough new RBCs to replace the ones already in your blood. Some viral It is an infectious diseases, such as parvovirus B19, can cause an aplastic crisis. These crises cause sudden paleness and weakness.
- Acute The chest. syndrome: This is the leading cause of hospitalization and death in people with SCD. It causes The chest. It is a pain., cough, fever, low blood oxygen, and abnormal substances accumulating in the lungs (lung infiltrates). Acute The chest. syndrome can follow VOCs.
- Hemolytic crisis: This happens when large numbers of RBCs are destroyed over a short time. It causes a sudden drop in hemoglobin levels (anemia).
There are other, less frequent types of crises.
You can have more than one type of crisis at a time.
The most common symptoms of a crisis are:
- excruciating bone It is a pain.
- The chest. It is a pain. and The breath was very thin.
- severe It is an infectious diseases (usually in children)
- Anemia is severe.
- weakness and low blood pressure
- Loss of consciousness.
- yellowing of the skin, eyes, or inside of mouth (There is a problem of jaundice.)
- severe organ damage, including stroke
These symptoms can develop over a period of time.
A VOC, which usually precedes other complications, can cause It is a pain. in the following body parts:
- The legs are long.
- The knees.
- The chest.
- The abdomen is large.
Is sickle cell crisis a medical emergency?
You should get treatment for a severe crisis immediately.
Keep a printed copy of your medical records, It is a pain. management plan, and a list of all your medications to bring with you to the medical facility.
If you have any of the following symptoms, you should immediately go to an urgent care facility.
- The temperature is at least 101F.
- The breath was very thin.
- The chest. It is a pain.
- There is abdominal swelling.
- There was a seizure.
- There is a severe headaches.
- sudden weakness
- decreased consciousness
- a It is a pain.ful erection that lasts more than 4 hours
- There is a problem of jaundice.
If you experience any of the following, you should call a doctor.
- It is a pain. anywhere in the body that won’t go away with home treatment
- any sudden vision issues
“You can’t prevent all crises, but you can minimize them.”
- It is advisable to drink at least eight glasses of water a day.
- dressing warmly in It is cold and carrying an extra layer just in case
- Avoid mountain climbing or air flights in an unpressurized cabin.
- Moderate exercise is sticking to light.
- paying attention to your stress levels
- washing your hands often to avoid It is an infectious diseases
- being sure to get all recommended vaccinations, including flu and coronavirus shots and boosters
- taking folic acid supplements to prevent anemia
- avoiding Alcohol. and tobacco products
Taking all recommended medications on time is a must.
“There are some crises that don’t warrant a trip to the emergency room. Home management is important, but it is important to get immediate medical attention if home treatment doesn’t work out.”
Home management is included.
- over-the-counter (OTC) It is a pain. relievers
- heating pads
- drinking a lot of water.
- Warm baths.
- The affected area has a massage.
If home management doesn’t work, a doctor will likely prescribe you stronger medications for It is a pain.. In addition, they’ll check for an underlying It is an infectious disease or dehydration that might be triggering the crisis. They may also give you intravenous (IV) fluids. In very severe cases, you may need a blood transfusion.
The FDA approves certain medications to reduce the number of VOCs.
- Hydroxyurea is a drug.
- L-glutamine is a drug.
- Adakveo is a crizanlizumab.
- voxelotor (Oxbryta)
There is a potential cure for the disease.
A sickle cell crisis is a very It is a pain.ful complication of SCD. It has many triggers, most of which cause constriction of your blood vessels, resulting in the clumping of blood cells in the capillaries.
You can treat mild It is a pain. at home, but more severe cases require immediate medical attention. You can prevent sickle cell crises by avoiding their triggers.