1. Simvastatin oral tablet is available as a brand-name drug and a generic drug. Brand name: Zocor.
  2. An oral suspension and an oral tablet are the two forms of simvastatin.
  3. Simvastatin is used to lower cholesterol. It can reduce the risk of The heart disease is very serious..

  • Myopathy and rhabdomyolysis warning: Simvastatin and other statin drugs can sometimes cause myopathy (muscle disease) or immune-mediated necrotizing myopathy (IMNM). They can even cause rhabdomyolysis (severe muscle breakdown). Rhabdomyolysis can lead to The kidneys fail.. You have an increased risk of each condition if you:
    • Are they a person older than 18?
    • Are they female?
    • Have a disease of the kidneys.
    • Have low thyroid function.
    • Take high amounts of this drug.
    • Take this drug with other drugs.

If you experience something, tell your doctor.

  • There is unexplained muscle weakness.
  • There is persistent muscle pain.
  • “When this drug is stopped, it doesn’t go away the muscle pain.”
  • There is abdominal pain.
  • There is a high degree of There is a high degree of fever..
  • Dark urine.
  • Warning for liver disease and alcohol misuse: People with active liver disease should not use simvastatin. People with a history of alcohol abuse or liver disease should discuss the risks of this drug with their doctor. For people with these conditions, simvastatin can increase the risk of serious liver injury.

Simvastatin is a drug used for cardiovascular disease. It comes in two forms. Both forms are taken with saliva.

Simvastatin oral tablet is available as the brand-name drug Zocor. It’s also available as a generic drug. Generic drugs usually cost less than the brand-name version. In some cases, they may not be available in every strength or form as the brand-name drug.

Why it’s used

The oral tablet is used forvastatin.

How it works

Simvastatin belongs to the drug class known as HMG-CoA reductase inhibitors, also called statins. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.

Statins work to reduce cholesterol. They reduce the amount of cholesterol in the body. High cholesterol and triglycerides are associated with increased risk.

  • The heart disease is very serious.
  • stroke
  • A heart attack.

Statins are usually used with lifestyle changes.

Simvastatin can cause other side effects.

More common side effects

simvastatin can have more common side effects.

  • There is a throbbing head.
  • nausea
  • stomach ache
  • It is a problem of the colon.
  • There is pain in the muscles or weakness.
  • Joint pain.
  • The respiratory infections.

Serious side effects

If you have serious side effects, call your doctor. If you think you are having a medical emergency, call the emergency room. There are serious side effects and their symptoms.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we can not guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare professional who knows your medical history.

Simvastatin can interact with other drugs. An interaction is when a substance changes the way a drug works. This can cause the drug to work differently.

Your doctor should keep a close eye on your medications. Tell your doctor about all your medication and supplements. Talk to your doctor or pharmacist about how this drug might interact with other drugs.

There are drugs that can cause interactions with simvastatin.

Strong CYP3A4 Inhibitors

The drugs block the absorption of simvastatin. This can cause your body to have high levels of the drug. It can increase side effects.

These drugs should not be used with simvastatin. If treatment with these drugs is required, the use of simvastatin must be on hold during the course of treatment. Examples of these drugs include:

  • It is a drug called ketoconazole.
  • Itraconazole is a drug.
  • voriconazole is a drug.
  • Posaconazole is a drug.
  • erythromycin is a drug.
  • clarithromycin.
  • telithromycin
  • The cyclosporine is a drug.
  • danazol is a drug.
  • nefazodone is a drug.
  • telaprevir is a drug.
  • ritonavir is a word.
  • tipranavir
  • Indinavir is a drug.
  • fosamprenavir is a drug.
  • darunavir is a drug.
  • Atazana is a drug.
  • nelfinavir
  • cobicistat

Other cholesterol-lowering drugs

Simvastatin can increase the risk of myopathy and rhabdomyolysis. If you use these drugs with simvastatin, your doctor may lower your dose. These drugs can be examples.

The Food and Drug Administration (FDA) reports that, according to research, with Is there any substance in it that is niacin?, the incidence of myopathy and rhabdomyolysis is higher when the drug is taken in larger doses and in people of Chinese descent.

Calcium channel blockers and other drugs that increase risk for myopathy or rhabdomyolysis

simvastatin can increase the risk of myopathy. Your doctor may lower your simvastatin dose. Calcium channel blockers are examples.

Do not take more than 10 mg of simvastatin with Diltiaquine or It is called verapamil., or more than 20 mg of simvastatin with Amlodipine is a drug..

Other drugs increase the risk ofrhabdomyolysis.

Heart drug

Digoxin is used to treat heart failure and arrhythmias. Taking simvastatin with digoxin can increase levels of digoxin in your body. If you’re taking both drugs, your doctor may want to monitor your digoxin level more closely.

Gout drug

Colchicine is a drug used to treat gout. Using simvastatin with colchicine can increase the risk of both myopathy and rhabdomyolysis.

Warfarin (blood thinner)

When taken with warfarin, simvastatin can increase the blood-thinning effects of warfarin. This can lead to an increased risk of bleeding. Your doctor may want to monitor your warfarin level more closely if you’re taking these two drugs at the same time.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we can not guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare professional about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.

This drug has several warnings.

Alcohol warning

People with a history of alcohol misuse should not take this drug. simvastatin can increase the risk of serious injury to the liver.

Food interaction warning

Take simvastatin without the use of grapefruit juice. simvastatin levels can be increased by drinking a lot of segulle juice.

Warnings for people with certain health conditions

For people with low thyroid function (hypothyroidism) or diabetes: Simvastatin and other statin drugs can sometimes cause rhabdomyolysis. Having hypothyroidism or diabetes raises your risk for this condition. Other risk factors include:

  • Being an older adult.
  • Being female.
  • Having a disease.
  • Drugs that interact with simvastatin are used.

If you experience something, tell your doctor.

  • There is unexplained muscle weakness.
  • The pain in the muscles.
  • There is a lot of There is a lot of diarrhea..
  • There is a high degree of There is a high degree of fever..
  • Dark urine.

For people with liver disease: People with active liver disease, such as cirrhosis or hepatitis, should not use simvastatin.

Warnings for other groups

For pregnant people: In July 2021, the FDA requested that statins no longer be labeled as “contraindicated” in pregnancy. The FDA still recommends that most patients discontinue statins when they become pregnant. The contraindication was removed as the choice to continue a statin should be patient-specific with the pros and cons weighed by both the doctor and the patient. The FDA has requested that manufacturers update their package inserts to reflect the change. As of now, there is no deadline by which all manufacturers must update their package inserts.

“Thevastatin is important for the baby’s development.”

“If you are pregnant and need treatment for high cholesterol, talk to your doctor. They can discuss other options during the baby’s birth.”

If you become pregnant while taking this drug, call your doctor.

For people who are nursing: It isn’t known if simvastatin enters breast milk. However, because of the risk of severe side effects, this drug should not be used during nursing. Talk with your doctor about other cholesterol treatment options while nursing.

For people of Chinese descent: The risk of myopathy and rhabdomyolysis is higher when the drug is taken with Is there any substance in it that is niacin? in larger doses. In addition, the FDA reports that, according to research, the incidence of myopathy is higher in people of Chinese descent. For more information about this higher occurrence, talk with your doctor.

There are no possible dosages or forms included here. How often you take it depends on:

  • Your age.
  • The condition is being treated.
  • How bad is your condition?
  • You have other medical conditions.
  • How do you react to the first dose?

Drug forms and strengths

Generic: Simvastatin

  • Form: oral tablet
  • Strengths: 5 mg, 10 mg, 20 mg, 40 mg, 80 mg

Brand: Zocor

  • Form: oral tablet
  • Strengths: 5 mg, 10 mg, 20 mg, 40 mg

Dosage for high cholesterol

The adult dosage is 18 years and older.

  • Typical starting dosage: Simvastatin is often started at 10–20 mg per day. However, the dosage may range from 5 mg to 40 mg per day. You should take this drug once a day in the evening.
  • Dosage increases: Your doctor will gradually adjust your dosage if needed.

The child dosage is 10 to 17 years old.

  • Typical starting dosage: 10 mg per day.
  • Note: Doses above 40 mg per day have not been studied in this age group.

Child dosage (ages 4–9 years)

  • Typical starting dosage: 5 mg per day.
  • Note: Doses above 20 mg per day have not been studied in this age group.

The child dosage is 0–4 years.

The medication has not been studied in children under 4 years old.

Dosage for reducing the risk of The heart disease is very serious. and A heart attack. and stroke in people with The heart disease is very serious.

The adult dosage is 18 years and older.

  • Typical starting dosage: Simvastatin is often started at 10–20 mg per day. However, the dosage may range from 5 mg to 40 mg per day. You should take this drug once a day in the evening.
  • Dosage increases: Your doctor will gradually adjust your dosage if needed.

The child dosage is 10 to 17 years old.

  • Typical starting dosage: 10 mg per day.
  • Note: Doses above 40 mg per day have not been studied in this age group.

The child dosage is 0 to 9 years old.

The medication has not been studied in children under 10 years old.

Special dosage considerations

  • For people with kidney disease: Having kidney disease may affect your dosage. People with advanced kidney disease usually require a lower dosage. Talk with your doctor about your treatment with simvastatin if you Have a disease of the kidneys..
  • For people with liver disease: If your liver isn’t working well, more of this drug may stay in your body longer. This puts you at increased risk of side effects. If you have active liver problems, you should not use this medication.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we can not guarantee that this list includes all possible dosages. This information is not a substitute for medical advice. Always speak with your doctor or pharmacist about dosages that are right for you.

“Long-term treatment with simvastatin is done. It comes with serious risks if you don’t take it as prescribed.”

If you don’t take it at all or stop taking it: If you have high cholesterol and don’t take your simvastatin, you risk having increased cholesterol levels, developing The heart disease is very serious., and having a A heart attack. or a stroke.

If you don’t take it on schedule: Not taking simvastatin every day, skipping days, or taking doses at different times of the day may also increase your risk for high cholesterol levels, A heart attack., or stroke.

If you miss a dose: If you miss a dose, take the next dose as scheduled. Do not double your dose.

How can I tell if the drug is working: Your cholesterol and triglyceride levels should be within healthy levels while taking it.

If your doctor prescribes simvastatin, keep these considerations in mind.

General

  • simvastatin can be taken with or without food. It may be possible to reduce nausea by taking it with food.
  • “simvastatin can be taken in the evening to maximize its effects. The body’s cholesterol production is highest at night.”

Storage

  • The tablets should be kept in a container between 41F and 86F.
  • The tablets should be kept in a container that is light- resistant.

Refills

“A prescription is not required. You don’t need a new prescription for this medication to be changed. Your doctor will write the number of refill you authorize.”

Travel

Traveling with your medication.

  • Carry your medication with you. Never put it in a checked bag. It should be in your carry-on bag.
  • “Don’t worry about the machines. They won’t hurt your medication.”
  • You may need to show the pharmacy label to the airport staff. Carry the original container with you.
  • Do not put this medication in your car or leave it in the car. It is very hot or very cold when this is happening.

Clinical monitoring

“simvastatin can affect your body’s organs, so your doctor will want to make sure it isn’t affecting you. A baseline test is a test that is repeated in a few months. They may do more tests during treatment.”

Are there any alternatives?

There are other drugs that can be used to treat your condition. Some may be better suited for you. Discuss with your doctor if there are other drug options that may work for you.

Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or other healthcare professional before taking any medication. The drug information contained here is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.