If you have a certain kind of cancer, your doctor may suggest Tibsovo as a treatment option.

Some adults use a prescription medication called tbisovo to treat certain types of cancer.

The cancer being treated must have a specific genetic abnormality.

The active ingredient in tbisovo is ivosidenib. An active ingredient is what makes a drug work.

This article describes the dosages of Tibsovo, as well as its strength and how to take it. To learn more about Tibsovo, including details about the cancers it’s used to treat, see this in-depth article.

Note: The chart below highlights Tibsovo’s dosage basics. Be sure to read on for more details. And keep in mind that this article covers Tibsovo’s standard dosage schedule, which is provided by the drug’s manufacturer. But always follow the dosing instructions your doctor prescribes.

Tibsovo form Tibsovo strength Usual dosage
oral tablet 250 milligrams (mg) per tablet 500 mg once per day

The section describes the common dosage information. Your doctor will discuss the instructions for the medication with you. Your doctor will tell you the correct amount of Tibsovo to take.

What is Tibsovo’s form?

You can take a tablet called Tibsovo.

What strength does Tibsovo come in?

250 milligrams is the strength of tbisovo.

What are the usual dosages of Tibsovo?

The recommended dose of Tibsovo is usually the first thing your doctor will start you on. They can adjust your dose over time. They will prescribe the smallest dose that will provide the desired effect.

The information below describes dosages that are commonly used or recommended. But be sure to take the dosage your doctor prescribes for you. They’ll determine the best dosage to fit your needs.

Dosage for acute myeloid leukemia

The recommended dosage of Tibsovo for Acute myeloid leukemia is a type of leukemia. is 500 mg (two 250-mg tablets) taken by mouth once per day.

Dosage for bile duct cancer

The recommended dose of Tibsovo for bile duct cancer is 500 mg (two 250-mg tablets) taken by mouth once per day.

Is Tibsovo used long term?

It is usually a long-term treatment. If you and your doctor determine that Tibsovo is safe and effective for you, you will likely use it for a long time.

If you are taking Tibsovo for leukemia, your doctor will recommend taking it for at least 6 months to see if it works for you. The manufacturer does not recommend bile duct cancer treatment.

If you have a serious side effect from the treatment, your doctor may stop it.

Dosage adjustments

In some cases, your doctor may recommend a lower dose of Tibsovo.

For example, some medications may increase the amount of Tibsovo in the body. This can increase the risk of side effects. If you take medications that can interact with Tibsovo this way, your doctor may recommend a Tibsovo dose decrease.

In addition, if you have certain side effects from Tibsovo, your doctor may recommend decreasing your dose of Tibsovo. This includes long QT syndrome, which is a heart rhythm problem, and any other side effects that are serious.

If you have questions about the best way to take Tibsovo, you should talk to your doctor.

The amount of Tibsovo you are prescribed may be affected by a number of factors. These include:

  • There are side effects from taking Tibsovo.
  • You can take other medications that are not related to Tibsovo.

You will take your dose by mouth. If you want to take your dose without food, you should avoid eating high-fat food. This can cause the drug to be released into the body too quickly, increasing your risk of side effects.

You should take your entire dose of Tibsovo. Do not chew the tablets.

“If you vomit after taking Tibsovo, don’t take another dose. Instead, take your next dose the next day.”

For information on Tibsovo expiration, storage, and disposal, see this article.

Accessible drug containers and labels

“If you can’t read the prescription label on your medication, you should tell your doctor or pharmacist. Some pharmacies may provide medication labels.”

  • Large print or use of blind.
  • You can use a code on a phone to change the text to sound.

“If your current pharmacy doesn’t offer accessibility features, your doctor or pharmacist may be able to recommend a new pharmacy.”

Let your pharmacist know if you have trouble opening bottles. They may be able to deliver Tibsovo in a container. It is possible that your pharmacist has some tips that can make it easier to open the drug container.

If you miss a dose, you should take it immediately, but it depends on when you remember. If you missed the dose, take it at the scheduled time. Wait until the scheduled time to take a dose is over. Take two doses of Tibsovo in a day.

If you missed a dose of Tibsovo, you should talk to your doctor or pharmacist about when to take your next dose. They can tell you when to take your next dose of medication.

If you need help remembering to take your dose of Tibsovo on time, try using a medication reminder. This can include setting an alarm or downloading a reminder app on your phone.

Do not use more than your doctor prescribes. Side effects can be serious if you use more than this.

What to do in case you take too much Tibsovo

Call your doctor right away if you think you’ve taken too much Tibsovo. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.

The dosages provided by the drug manufacturer are described in the sections above. If your doctor recommends it, they will prescribe the correct amount of Tibsovo.

Remember, you should not change your dosage of Tibsovo without your doctor’s recommendation. Only take Tibsovo exactly as prescribed. Talk with your doctor if you have questions or concerns about your current dosage.

Some questions you may want to ask your doctor.

  • Will my other drugs affect my dose?
  • Can you reduce my dose of Tibsovo if I have side effects from the medication?
  • Will my other conditions affect my dose of Tibsovo?


“Can I try a higher dose of the drug if it isn’t working for me?”



“If your doctor doesn’t think that Tibsovo is helping to treat your cancer, he won’t increase your dose. The cancer won’t respond to the drug if the dosage is increased. Your risk of side effects could increase if you have a higher dosage.”

“If you are taking the drug and it doesn’t seem to work for you, your doctor will probably suggest you stop. They will recommend a new treatment option for you if it is possible to treat your cancer.”

The Healthline Pharmacist TeamAnswers represent the opinions of our medical experts. All content is strictly informational and should not be considered medical advice.

Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.