If you have a certain kind of cancer, your doctor may suggest Tibsovo as a treatment option.

Some adults use a prescription drug called tbisovo to treat certain types of cancer.

The cancer can be treated with tbisovo until the side effects become intolerable.

You can take a tablet called Tibsovo. The active ingredient is ivosidenib. An active ingredient is what makes a drug work.

For more information about Tibsovo, including details about its uses, see this in-depth article on the drug.

Mild to serious side effects can be caused by Tibsovo. Continue reading to learn more.

Mild to serious side effects may occur during treatment.

Listed below are just a few of the more common side effects reported in studies of Tibsovo. These side effects can vary depending on what condition the drug is being taken to treat.

More common side effects in people taking Tibsovo for Acute myeloid leukemia is a type of leukemia. include:

The side effects explained section is where you can learn more about this side effect.

More common side effects in people taking Tibsovo for bile duct cancer include:

Mild side effects can be caused by taking Tibsovo.

Mild side effects have been reported with Tibsovo.

“These side effects should be temporary. Some may be easy to manage. If you have any symptoms that bother you, talk to your doctor or pharmacist. Unless your doctor recommends it, don’t stop taking Tibsovo.”

Tibsovo may cause mild side effects other than the ones listed above. See the Tibsovo prescribing information for details.

Note: After the Food and Drug Administration (FDA) approves a drug, it tracks side effects of the medication. If you’d like to notify the FDA about a side effect you’ve had with Tibsovo, visit MedWatch.

There are serious side effects that can happen when taking Tibsovo. Some serious side effects are more likely than others.

There have been serious side effects reported with Tibsovo.

* Tibsovo has a boxed warning for this side effect. This is the most serious warning from the Food and Drug Administration (FDA). To learn more, see the “Side effects explained” section below.
† To learn more about this side effect, see the “Side effects explained” section below.

If you develop serious side effects while taking Tibsovo, call your doctor. If the side effects seem life threatening or you think you have a medical emergency, immediately call the emergency number.

Some of the side effects of Tibsovo may be explained.

Differentiation syndrome

Tibsovo has a boxed warning for a risk of differentiation syndrome. A boxed warning is the most serious warning from the Food and Drug Administration (FDA). It alerts doctors and patients about drug effects that may be dangerous.

Differentiation syndrome can affect your blood cells. It can cause organ failure or even death in rare cases.

In studies of Tibsovo, this syndrome was a commonly reported side effect in people taking the drug to treat Acute myeloid leukemia is a type of leukemia.. You can develop it right after your first dose or any time within the first 3 months of starting treatment.

There are possible symptoms that may be caused by differentiation syndrome.

What might help

If you notice symptoms of differentiation syndrome while taking Tibsovo, seek emergency medical care immediately. You’ll likely need treatment and monitoring in a hospital. Treatment may include receiving a corticosteroid such as dexamethasone.

Your doctor will determine if it is safe for you to continue taking Tibsovo after treatment for differentiation syndrome.

Guillain-Barré syndrome

In rare cases, Tibsovo can cause Guillain-Barré syndrome. This is a condition that affects your nervous system.

Guillain-Barré syndrome can have symptoms.

What might help

If you notice symptoms of Guillain-Barré syndrome, you should contact your doctor. If your doctor confirms that you have this syndrome, they will stop treatment permanently. They will likely suggest treatments for Guillain-Barré syndrome and other diseases.

High level of leukocytes

Taking Tibsovo may cause a high level of leukocytes, a kind of white blood cell. This is known as leukocytosis.

“Leukocytosis doesn’t cause symptoms. Your blood can become thick if your level of leukocytes is high. This can affect blood flow, which can cause serious issues in rare cases.”

  • There is bleeding from your mouth, stomach, or intestines.
  • breathing problems
  • stroke
  • Vision problems.

What might help

Before and during treatment with Tibsovo, your doctor will order blood tests to check your leukocyte level. If your leukocyte level becomes too high, your doctor may prescribe you a drug called hydroxyurea. (Doxia, Hydrea). It can help lower your white blood cell count.

“If hydroxyurea doesn’t work to manage your leukocytosis, you may have to stop taking Tibsovo. When your leukocytes return to normal, they will likely have you resume treatment.”

Long QT syndrome

Tibsovo may cause an abnormal heart rhythm called long QT syndrome. This is a change to certain electrical activity in your heart.

Although this side effect was somewhat common in studies of Tibsovo, it didn’t always cause symptoms or complications. But in rare cases, it can cause more serious heart rhythm problems.

If you have long QT syndrome, your risk of abnormal heart rhythm may be higher.

  • Other medications can cause long QT syndrome.
  • They were born with a syndrome.
  • have frequent problems with your blood electrolyte levels
  • have heart failure

Your doctor may notice QT prolongation using a test called an electrocardiogram (EKG). In rare cases, long QT syndrome can cause symptoms, including:

What might help

Your doctor will check your blood electrolyte levels and order an EKG during Tibsovo treatment. They will use these tests to look for signs of an abnormal heart rhythm.

If you notice symptoms of long QT syndrome, call your doctor. If your doctor suspects you have long QT syndrome, they may suggest.

  • Trying a lower dose.
  • Treatment with Tibsovo can be stopped temporarily or permanently.

Allergic reaction

Like most drugs, Tibsovo can cause an allergic reaction in some people. But these reactions weren’t common in studies.

Mild to serious symptoms can be present.

What might help

If you have mild symptoms of an allergic reaction, such as a mild rash, call your doctor right away. To manage symptoms, they may suggest an over-the-counter antihistamine you take by mouth, such as Benadryl (diphenhydramine). Or they may recommend a product you apply to your skin, such as hydrocortisone cream.

If your doctor confirms you had an allergic reaction to Tibsovo, they will decide if you should continue taking it.

If you have symptoms of a severe allergic reaction, such as swelling or breathing problems, call 911 or your local emergency number right away. These symptoms could be life threatening and require immediate medical care.

If your doctor confirms you had a serious allergic reaction to Tibsovo, they may have you switch to a different treatment.

Keeping track of side effects

Keep notes on any side effects you are having during treatment. You can share this information with your doctor. This is helpful when you are starting to use a combination of treatments.

Side effect notes can include things.

  • What dose of drug did you take when you had the side effect?
  • How soon did you experience the side effect?
  • What are the symptoms you are having?
  • How did it affect your daily activities?
  • What other drugs were you taking?
  • Other information is important to you.

Sharing notes with your doctor will help them learn more about how Tibsovo affects you. If needed, they can use this information to adjust your treatment plan.

There are certain precautions to consider before taking Tibsovo. If these affect your decision on whether or not to use Tibsovo for your cancer, then so be it.

Boxed warning: Risk of differentiation syndrome

Tibsovo has a boxed warning for the risk of differentiation syndrome. A boxed warning is the most serious warning from the Food and Drug Administration (FDA).

In studies of Tibsovo, this syndrome was a commonly reported side effect in people taking the drug to treat Acute myeloid leukemia is a type of leukemia.. This syndrome is a serious condition that affects your blood cells. Without treatment, it can cause organ failure or even death in rare cases.

To learn more, see the “Side effects explained” section above.

Other warnings

If you have a medical condition that affects your health, it may not be right for Tibsovo. Before starting Tibsovo, you should talk to your doctor about your health history. The list has factors to consider.

Electrolyte problems. Treatment with Tibsovo can cause a heart rhythm condition called long QT syndrome. If you have electrolyte problems, such as low potassium or low sodium levels, you may have a higher risk of this Tibsovo side effect. Tell your doctor about any electrolyte problems you have. This will help them determine whether Tibsovo is safe for you to take.

Heart problems, including long QT syndrome. Treatment with Tibsovo can cause a heart rhythm condition called long QT syndrome. If you have existing heart problems, you may have a higher risk of this Tibsovo side effect. And if you already have long QT syndrome, taking Tibsovo could worsen your condition. Before you start taking Tibsovo, tell your doctor about any heart problems you have. They can let you know if Tibsovo is a good treatment option for you.

Liver problems. People with mild or moderate liver problems can usually take Tibsovo safely. But it’s not known if it’s safe for people with severe liver problems to take Tibsovo. If you have liver problems, talk with your doctor before beginning treatment with Tibsovo. They can determine the severity of your liver problems and then advise whether it’s safe for you to take Tibsovo.

Nervous system problems. In rare cases, taking Tibsovo can cause nervous system side effects. These can include new nervous system problems, such as Guillain-Barré syndrome. But if you already have a nervous system problem, taking Tibsovo could worsen your condition. Tell your doctor if you have this kind of condition. They can let you know whether Tibsovo is safe for you to take.

Allergic reaction. If you’ve had an allergic reaction to Tibsovo or any of its ingredients, your doctor will likely not prescribe Tibsovo. Ask them what other medications are better options for you.

Alcohol and Tibsovo

There isn’t a known interaction between Tibsovo and alcohol.

But alcohol can raise your risk of or worsen certain side effects from Tibsovo, including There is a lot of There is a lot of There is a lot of diarrhea…, nausea, and low energy.

Talk to your doctor about the risks and benefits of drinking while taking Tibsovo.

Pregnancy and breastfeeding while taking Tibsovo

It is not known if it is safe to take Tibsovo while pregnant. It is thought that doing so could cause harm.

If you are pregnant or planning to become pregnant, it is important to talk with your doctor. They can discuss the risks and benefits of taking a treatment like Tibsovo.

It is not safe to take tbisovo while breastfeeding. You should not breastfeeding after your last dose of the drug. Talk to your doctor about safe ways to feed your child.

Side effects can be caused by taking Tibsovo. If you are considering treatment with Tibsovo, talk to your doctor about possible side effects. Ask questions that will help you feel more comfortable. Some examples will get you started.

  • Will I take a lower dose if I have side effects?
  • How do the side effects of Tibsovo compare to other drugs?
  • Does Tibsovo cause long-term side effects?

Q:

Is it possible that other medications will increase my risk of side effects with Tibsovo?

Anonymous

A:

It is possible. Certain medications can interact with Tibsovo, which can raise your risk of side effects. These medications are used.

The drugs on the list are not all that may increase your risk of side effects. Inform your doctor and pharmacist of any medications you take before you start taking Tibsovo. They can check for any interactions with Tibsovo.

The Healthline Pharmacist TeamAnswers represent the opinions of our medical experts. All content is strictly informational and should not be considered medical advice.

Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.