If you have type 1 or type 2 diabetes, your doctor might prescribe Toujeo. It’s a prescription diabetes medication used in adults and some children.

To learn more about diabetes and how Toujeo is used, see the “Is Toujeo used for diabetes?” section below.

Toujeo basics

Toujeo contains insulin glargine, which is a biologic medication. (A biologic is a drug made from parts of living organisms.) Toujeo is a long-acting insulin. It comes as a liquid solution that you’ll inject under your skin.

A biosimilar medication is not currently available for Toujeo. (Biosimilars are like generic drugs. But unlike generics, which are made for nonbiologic drugs, biosimilars are made for biologic drugs.)

Lantus, Basaglar, Semglee, and Rezvoglar are the brand-name drugs that contain the drug, Insulin glargine. The Toujeo contains a higher dose of the drug. Your doctor or pharmacist can give you more information about the drugs.

Read on to learn more about the side effects of Toujeo.

Toujeo comes as two pens: Toujeo SoloStar and Toujeo Max SoloStar. Both forms of the drug contain the same active ingredient, insulin glargine.

The following chart shows the pens against each other.

Toujeo SoloStar Toujeo Max SoloStar
Total amount of insulin 450 units per pen 900 units per pen
Dose increment (smallest possible dose change) 1 unit 2 units
Maximum dose 80 units per injection 160 units per injection

If you need to inject more than 20 units of insulin per day, your doctor will likely prescribe Toujeo Max SoloStar.

If your doctor changes your pen from Toujeo SoloStar to Toujeo Max SoloStar, they’ll tell you what dose to inject. You might need to increase or decrease your dose by one unit. (See “How is Toujeo used?” below for more information about how to inject this drug.)

You may wonder if Toujeo is similar to Lantus. Both medications are prescribed to treat type 1 and type 2 diabetes in adults and children ages 6 years and older. Toujeo and Lantus also contain the same active ingredient, insulin glargine.

There are important differences between Toujeo and Lantus. For more information about how the two drugs compare, see this in-depth article.

You might like to learn about other alternatives to Toujeo, such as Basaglar. Make sure to talk with your doctor about the drug that’s best for your condition. The chart provides information about how Toujeo compares with some alternatives:

Active ingredient Conditions approved for Ages approved for Detailed comparison
with Toujeo
Toujeo insulin glargine type 1 and type 2 diabetes adults and children
ages 6 years and older
Tresiba insulin degludec type 1 and type 2 diabetes adults and children
ages 1 year and older
Toujeo vs. Tresiba
Basaglar insulin glargine type 1 and type 2 diabetes adults and children
ages 6 years and older
Toujeo vs. Basaglar
Levemir insulin detemir type 1 and type 2 diabetes adults and children
ages 2 years and older
Toujeo vs. Levemir

Your doctor will recommend the dosage of Toujeo that’s right for you. Below are commonly used dosages, but always take the dosage your doctor prescribes.

Forms and strength

Toujeo comes as a liquid solution that contains 300 units of insulin glargine per milliliter of solution (units/mL). It comes in a prefilled pen that delivers a specific number of insulin units.

Toujeo SoloStar and Toujeo SoloStar Max

The Toujeo is available in two different styles. Depending on how many units of glargine you need, your doctor will prescribe either the Toujeo SoloStar or Toujeo SoloStar Max pen.

“Attach pen needles to use either of these pens. Toujeo is not in a container. This isn’t how the solution is supplied.”

See the “How do Toujeo SoloStar and Toujeo Max SoloStar differ?” section above for details about each type of pen.

Recommended dosage

Your doctor will tell you exactly how many units of Toujeo you’ll inject as a starting dose. This varies depending on whether you have type 1 or type 2 diabetes. Your doctor will also use your blood sugar levels and treatment goals to calculate your dose. And they may adjust your dose over time.

You will inject Toujeo at the same time every day. Some other products follow twice daily dosing.

If you are already taking a different type ofinsulin, your doctor will tell you the dose to inject. It may be different than your other medication.

Before you inject, make sure to check the label of your products. It is possible to mix up your insulin doses.

For more in-depth information about Toujeo’s dosages, see this detailed article.

Questions about Toujeo’s dosage

  • What if I miss a dose of Toujeo? If you miss a dose of Toujeo, take it as soon as you remember. But if you’re close to taking your next scheduled dose, skip the missed dose. If you’re unsure when to take Toujeo after missing a dose, talk with your doctor or pharmacist. It might help to download a reminder app or set an alarm each day to help you remember to inject Toujeo.
  • Will I need to use Toujeo long term? Diabetes is a long lasting condition, so you might need to take Toujeo long term. To find out how long you’ll need to take Toujeo, talk with your doctor.
  • How long does Toujeo take to work? Toujeo is a long-acting insulin. It takes about 6 hours to start working after injection. Its effects may last for more than 36 hours after injection.

Mild or serious side effects may occur with Toujeo. The side effects of Toujeo are described in the lists below. All possible side effects are not included in these lists.

The side effects of a drug can depend on other factors.

  • Your age.
  • You have other health conditions.
  • You take other drugs.

Your doctor or pharmacist can tell you more about the potential side effects of Toujeo. They can also suggest ways to help reduce side effects. You can also read this article for in-depth information about Toujeo’s side effects.

Mild side effects

Here’s a short list of some of the mild side effects that Toujeo can cause. To learn about other mild side effects, talk with your doctor or pharmacist or read Toujeo’s prescribing information.

There are some mild side effects of Toujeo that have been reported.

  • The cold.
  • The upper airway is prone to infections.
  • Injection site reaction
  • lipodystrophy or localized cutaneous amyloidosis (skin conditions that cause pits, thickening, or lumps in the skin around your injection site)
  • It is itchy.
  • edema (fluid buildup in the body)
  • There is a rash.*
  • mild hypoglycemia (low blood sugar)*
  • weight gain

The side effects of many drugs can be gone in a few days. If they become intolerable, talk to your doctor or pharmacist.

Serious side effects

There are serious side effects from Toujeo, but they are not common. If you have serious side effects, call your doctor. If you think you have a medical emergency, you should call the emergency number.

There have been serious side effects of Toujeo.

The side effect focus section gives more information about this side effect.

Side effect focus

There are some side effects of Toujeo.

Weight gain

When taking insulin, including Toujeo, you might gain weight. Weight gain can occur when you start Toujeo treatment because the drug may cause you to urinate less than you did before.

Diabetes causes you to urinate more often than usual. When your blood sugar is too high, your body gets rid of some excess sugar through your urine. Urinating frequently means you lose more water from your body than usual. This decreases your “water weight.”

“When you take Toujeo and your diabetes is under control, you will usually stop urinating. Your body won’t be getting rid of as much water, so you can gain weight.”

Toujeo can also lead to weight gain because it affects your metabolism. Insulin decreases the breakdown of fats and protein in your body. It also activates the production of certain fats and proteins. This can make you gain weight.

What can help?

A healthy diet and regular exercise can help prevent weight gain. This can also help you manage your blood sugar levels.

Talk to your doctor if you are concerned about gaining weight. They can help you with your weight.


A There is a rash. might appear where you inject Toujeo. A There is a rash. may be a symptom of an allergic reaction or an Injection site reaction.

Injection site reactions are usually mild and can cause other symptoms, such as redness or discoloration.

If you have a There is a rash. on your entire body or most of your body, it might be a symptom of a severe allergic reaction. Other symptoms of an allergic reaction may include trouble breathing, fast heart rate, or sweating. See “Allergic reaction” below for details.

What can help?

If you think you have an allergic reaction to Toujeo, you should contact your doctor. If you are having trouble breathing, a fast heart rate, or sweating that is excessive, you should get emergency medical attention.

An Injection site reaction is usually mild and goes away over time. If you have a There is a rash. that doesn’t go away with time, talk with your doctor or pharmacist. They may suggest other injection techniques to help prevent There is a rash.es at the injection site.


Hypoglycemia (low blood sugar) is the most common side effect of Toujeo. If your blood sugar drops too low, it can be life threatening.

Your doctor will tell you about the symptoms of hypoglycemics. Some symptoms include:

  • feeling shaky, nervous, anxious, or irritable
  • sweating
  • There is a headaches and confusion.
  • feeling unwell or dizzy.
  • nausea
  • Problems with your eyesight.
  • There are balance problems.

If your blood sugar becomes very low or stays low for a long time, you may have more serious symptoms. These can include fainting and Seizures.. Rarely, severe hypoglycemia can cause death.

What can help?

To help prevent hypoglycemia, check your medication labels to make sure you inject the correct amount of insulin for each dose. If you’re taking different types of insulin, make sure to take the correct insulin at the correct time. Your doctor will tell you how to monitor your blood sugar levels and manage hypoglycemia if it occurs.

If you have a low blood sugar level, you should eat something that is high in sugar. The 15-15 rule is helpful for remembering how much sugar to take, as you can check your blood sugar 15 minutes later.

15 g of sugar can be examples.

Allergic reaction

Some people may have an allergic reaction to Toujeo.

A mild allergic reaction can include some symptoms.

A more severe allergic reaction is rare but possible. Symptoms of a severe allergic reaction can include a whole-body There is a rash. and swelling under your skin (typically in your eyelids, lips, hands, or feet). They can also include swelling of your tongue, mouth, or throat, which can cause trouble breathing.

If you have an allergic reaction to Toujeo, call your doctor. If you think you have a medical emergency, call the emergency number.

Find answers to questions about Toujeo.

Does Toujeo need to be stored in the refrigerator?

You should keep Toujeo pens in the refrigerator at a temperature of 36F to 46F (2C to 8C) until you are ready to use them. Do not store the drug in the freezer.

Before using pens for injections, you should let them come to room temperature. They should be able to get to a temperature of 86F (30C). The pen should be stored at a temperature that is at room temperature. You can keep pens at room temperature for 56 days.

What’s the duration of action for Toujeo? Is it a fast-acting insulin?

After the injection, Toujeo starts working. Its effects may last for more than 36 hours.

Toujeo isn’t a fast-acting insulin. Its active ingredient, insulin glargine, is a long-acting insulin.

Are reviews available from people who’ve taken Toujeo?

You can browse the manufacturer’s site for reviews from people who’ve taken Toujeo. The website also provides other tools and resources for people taking Toujeo.

What is Toujeo’s shelf life? When does it expire after opening?

The shelf life of Toujeo depends on whether you allowed the pens to come to room temperature or not. The pens are safe to use until the packaging is expired. The Toujeo pen will be gone in 8 weeks.

How does Toujeo work?

Toujeo is a type of long-actinginsulin. It helps manage blood sugar by allowing cells in your body to take in sugar.

Toujeo is a mechanism of action of the drug. Mechanism of action is the way a drug works in your body.

Your doctor or pharmacist can give you more information about Toujeo.

Does Toujeo cause joint pain, diarrhea, or weight loss?

No, Toujeo doesn’t cause joint pain, diarrhea, or weight loss. But other diabetes medications might.

“If you are having any of the following, talk to your doctor or pharmacist. They can help you figure out what’s going on and how to deal with it.”

What is Toujeo’s half-life? How long does it take the drug to pass through the body?

Toujeo’s half-life is around 18 to 19 hours. A drug’s half-life is the amount of time it takes your body to clear half of one dose from your system.

After 5 half-lives, most drugs are gone from the body. The drug takes about 4 days to clear from your system, because it takes 18 to 19 hours for the half-life to end.

If you have questions about your treatment, you should talk to your doctor. They can give more information about Toujeo.

There are many factors that affect the cost of prescription drugs. What your insurance plan covers is one of the factors.

If you have questions about how to pay for your Toujeo prescription, talk with your doctor or pharmacist. You can also visit the manufacturer’s website to see if they have patient assistance options.

You can also check out this article to learn more about saving money on prescriptions.

Do not take more than your doctor prescribes. Taking more than this can cause serious side effects.

How much Toujeo is too much?

It is too much to take more than your prescribed dose. Your doctor will calculate the dose that you need. The amount of Toujeo that is considered too much can be different for each person.

Symptoms of overdose

There are symptoms of an overdose.

  • hypoglycemia (low blood sugar)
  • hypokalemia (low potassium level)
  • A coma.
  • Seizures.
  • The nervous system has damage.

What to do in case you take too much Toujeo

Call your doctor if you think you’ve taken too much Toujeo. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource. But if you have severe symptoms, immediately call 911 or your local emergency number. Or, go to the nearest emergency room.

Yes, Toujeo is used in adults and children ages 6 years and older with type 1 or type 2 diabetes. With type 1 diabetes, your pancreas doesn’t produce enough insulin to manage your blood sugar. If you have type 2 diabetes, the insulin that your body produces doesn’t work properly.

Toujeo is a type of long-acting insulin called insulin glargine. Insulin is made in the body by the pancreas. It manages blood sugar by allowing the muscle and fat cells in your body to take in sugar. Once the sugar is in the cells, your blood sugar decreases. Insulin also controls the production of sugar by the liver.

Your doctor may recommend other medications or ways of managing your diabetes, in addition to Toujeo. A balanced diet and exercising are two examples. You will likely need medication if you have type 2 diabetes.

Note: Toujeo isn’t prescribed to treat diabetic ketoacidosis (high levels of ketones in your blood or urine). Your doctor or pharmacist can provide more information about this.

Your doctor will explain how you should take Toujeo. They’ll also explain how much to take and how often. Be sure to follow their instructions.

Injecting Toujeo

You’ll inject Toujeo under your skin once per day, at the same time every day, using a prefilled pen. You’ll attach a needle to the pen before each injection.

Toujeo injection sites

You can inject Toujeo into a body part. Do not inject Toujeo in the same spot. You should be rotating injection sites. If you inject Toujeo into your belly, you should use your upper arm or thigh the next day. You can put it in a different part of your body.

Rotating injection sites lowers your risk of side effects such as lipodystrophy and localized cutaneous amyloidosis. These side effects can cause pits, thickening, or lumps in the skin around your injection site. Rotating sites also lowers your risk of Injection site reactions.

If you want to inject Toujeo into areas of skin that are pitted or have a lump, you should avoid it. It is also advisable to avoid areas that are hard. If you want to inject Toujeo under scars or damaged skin, you should do it elsewhere.

Taking Toujeo with other drugs

Your doctor might prescribe other diabetes medications along with Toujeo to help manage your blood sugar. This may include other types of insulin.

For type 1 diabetes, insulin is the only diabetes medication you’ll typically take. But your doctor might prescribe more than one type of insulin.

Rapid-acting and short-acting insulin products, such as insulin lispro (Humalog) and regular insulin (Humulin R), can be used with Toujeo. Toujeo is a type of long-acting insulin.

For type 2 diabetes, Toujeo may be prescribed with other medications to help manage your blood sugar. These medications might include:

Should I take Toujeo with food?

“You can take Toujeo with or without food. Taking Toujeo with or without food doesn’t affect how much medication your body takes”

Questions for your doctor

You may have questions about Toujeo. Discuss your concerns with your doctor.

Here are a few tips that might help you.

  • Before your appointment, write down questions, such as:
    • How will Toujeo affect my life?
  • Bring someone to your appointment will make you feel more comfortable.
  • “If you don’t understand something, ask your doctor to explain it.”

“Your doctor and other healthcare professionals are available to help you. They want you to get the best care possible. Don’t be afraid to ask questions or give feedback on your treatment”

When considering treatment with Toujeo, it is important to have a discussion with your doctor about your health and any medical conditions you may have.

If you are taking other medications, tell your doctor. Drugs can interfere with Toujeo. These are some considerations to discuss with your doctor.


Certain vaccines, foods, and other drugs can affect how your medication works. These effects are called interactions.

Toujeo can interact with a lot of drugs. These drugs are used.

The list does not include all drugs that may interact with Toujeo.

Before taking Toujeo, you should tell your doctor about all your medication. You should describe any vitamins, herbs, or supplements you take. Your doctor or pharmacist can tell you about any interactions these items may cause.


If you have a medical condition that affects your health, Toujeo may not be right for you. Before you take Toujeo, talk to your doctor about your health history. The factors to consider are listed below.

  • Hypoglycemia (low blood sugar). Hypoglycemia can occur when you’re changing from one insulin product to another. Make sure to read your medication labels carefully before injection to ensure you have the right dose. If you have an episode of hypoglycemia, your doctor may adjust your dose of Toujeo. Your doctor will tell you how to recognize symptoms of hypoglycemia and what to do. You can also see “What are Toujeo’s side effects?” above for details.
  • Allergic reaction. If you’ve had an allergic reaction to Toujeo or any of its ingredients, your doctor may not recommend Toujeo as a treatment option. Ask your doctor what other medications are better options for you.
  • Hypokalemia (low potassium level). Hypokalemia is a possible side effect of Toujeo. If you have risk factors for this condition, you may have a higher risk of severe hypokalemia with Toujeo. Risk factors include taking medications that can lower your potassium level, such as furosemide (Lasix) and indapamide. Your doctor may monitor your blood potassium levels more often than usual during Toujeo treatment. If you have severely low potassium, you may develop serious breathing problems and an irregular heart rate. This can be life threatening in severe cases. Make sure to tell your doctor if you have possible symptoms of this condition. They may stop your Toujeo treatment.
  • Heart failure and fluid buildup. If you have heart failure or edema, taking Toujeo with certain other diabetes medications can make your condition worse. This includes drugs called thiazolidinediones, such as pioglitazone (Actos) and rosiglitazone (Avandia). Your doctor will monitor your heart function if you’re taking Toujeo and a thiazolidinedione medication.

Toujeo and alcohol

Alcohol can have different effects on insulin, including insulin glargine, the active ingredient in Toujeo. It can either decrease or increase the effectiveness of insulin.

Alcohol could make Toujeo less effective for managing blood sugar. It is possible for alcohol to cause a dangerous condition.

Some factors affect how well Toujeo works. How much alcohol you have consumed and how much food you have eaten are included.

“Since you can’t predict how alcohol will affect your treatment, talk to your doctor about making sure that alcohol is safe for you to have Your doctor may need to know how much you drink. Before you adjust your dose of Toujeo, talk to your doctor.”

Pregnancy and breastfeeding

The drug Toujeo was not shown to cause harm to a pregnant person or fetus. More information is needed to say if Toujeo increases the risk of harmful effects when taken during pregnancy.

It is important to manage your diabetes during your pregnancies to avoid birth defects.

There is not enough information about breastfeeding. It is not known if Toujeo passes into breast milk.

If you are pregnant, breastfeeding or considering it, you should talk to your doctor to find out which diabetes medication is best for you. Your doctor can help you decide if Toujeo is worth the risk.

If you have questions about Toujeo, talk with your doctor or pharmacist. Your doctor can tell you about other treatments you can use for your diabetes. This article with a complete list of diabetes medications might also be helpful.

Some questions to ask your doctor about Toujeo.

  • What can I do to reduce my dose?
  • How can I not have any pain while injecting Toujeo?
  • How should I dispose of my expired or empty Toujeo pens?
  • What should I do if the liquid in my pen is cloudy?

You can learn more about the uses of Toujeo by subscribing to the Healthline type 2 diabetes newsletter. And you can learn from others living with type 2 diabetes and find more resources from the Bezzy T2D community.


If my doctor changes the number of units of Toujeo I should use, how often should I check my blood sugar?



Once you’re taking a stable dose of insulin, your doctor will recommend that you check your blood sugar level at least once daily. If your doctor adjusts your dosage of Toujeo, they’ll likely have you check your blood sugar level more often. (This could be two or three times a day.)

How often you check your blood sugar depends on your dose.

  • Any side effects you have had.
  • How well do you manage your blood sugar?

If you have questions about your blood sugar levels, talk to your doctor.

The Healthline Pharmacist TeamAnswers represent the opinions of our medical experts. All content is strictly informational and should not be considered medical advice.

Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.