Glucagon-like peptide-1 receptor agonists are used to treat type 2 diabetes.

They are injected under the skin. GLP-1 RAs are often used with other antidiabetic treatments.

There are several GLP-1 RAs on the market that have different schedules. They include:

  • Exenatide is a drug.
  • dulaglutide is a drug.
  • semaglutide is also available in tablets.
  • liraglutide is a drug.
  • Adlyxin is a drug called lixisenatide.
  • pramlintide is a medication
  • Tirzepatide is named after the man.

In 2022, the Food and Drug Administration (FDA) approved tirzepatide for the treatment of type 2 diabetes. According to the FDA press release, clinical trials suggest that tirzepatide may be more effective than other therapy options. This injectable is given once per week.

Pramlintide is an injection drug that is used for the treatment of type 2 diabetes. It is used with the shots for diabetes. It works the same as GLP-1 RAs.

These drugs can help with a number of things, including: delay gastric emptying, increase feelings of fullness, lower cholesterol, and lower blood pressure.

Administered drugs do not cause weight gain.

Because they decrease appetite, they may even contribute to weight loss in the range of 2.2 pounds (1 kg) to 6.6 pounds (3 kg). The amount of weight loss depends on multiple factors, such as:

  • diet
  • Exercise.
  • Other medications can be used.

GLP-1 RAs are good for people who are overweight or obese. They are often used with other drugs or with the drug insulin to reduce the chance of weight gain.

GLP-1 RAs are similar to administering insulin, in that they are prefilled pens. They are different by the duration of action.

There are no comparative trials that show how the choice of medication affects long-term patient outcomes.

A doctor will usually start you off with a low dose. This will be increased according to the desired effect.

Exenatide is the only agent that needs to be administered twice a day. The others are injected daily or weekly.

Many patients experience nausea, vomiting, and diarrhea. Over time nausea may be reduced by lowering the dose. It may happen less often with weekly agents.

Other side effects may include:

Some reports link acute pancreatitis with GLP-1 RAs, but there’s not enough data to establish a clear causal relationship. Research has explored other potential adverse effects on the pancreas, such as pancreatic cancer, but more evidence is needed to determine a link.

Local skin reactions may be caused by GLP-1 RAs. Some people using exenatide have reported a side effect.

Hypoglycemia is rare with GLP-1 RAs. Adding them to therapies that use the drug can increase risk.

There was an increase in medullary thyroid tumors in the studies. There is no similar effect in humans.

Doctors recommend contraceptives for people who may become pregnant while taking medication.

Allergic reactions

People can have allergies to GLP-1. There are signs of a life threatening allergic reaction.

  • breathing problems
  • facial swelling
  • Losing consciousness.
  • feeling lightheaded

If you experience any of the above signs after taking medication, call the emergency services.

People with type 2 diabetes may have lifestyle changes.

  • modifying diet
  • Losing 5 to 10 percent of body weight is possible for people with overweight or obese bodies.
  • 150 minutes of exercising a week.
  • Monitoring of blood sugars.
  • Adult women and adult men can only drink one drink per day.
  • If you smoke, you should not.

The diabetes plate method is commonly used for providing basic meal planning guidance and for its visual help.

A registered dietitian can help you to make a healthier diet. Individualized nutrition plans can be recommended by a dietitian.

Reducing your intake of sugars is necessary to improve your blood sugar management.

Choose the type of food you want:

  • “It’s a very dense food.”
  • high in fiber
  • minimally processed

Water is a substitute for sugar-sweetened beverages.

Eating foods with high levels of monounsaturated and polyunsaturated fats might lower your cardiovascular risk.

The cost of injected GLP-1 and pramlintide is high. There are no generic options currently available.

The price of these medications can be different by pharmacy and insurance. The prices in this list are estimates and may not correspond to the prices you receive at a pharmacy.

According to GoodRx, average prices are as follows:

  • Exenatide is a drug.: $954
  • dulaglutide is a drug.: $949
  • Semaglutide is a drug in the Ozempic.
  • Semaglutide is $1,936.
  • Semaglutide is $1058
  • The drug is called liraglutide (Saxenda) and it costs $1,630
  • The drug is called liraglutide (Victoza).
  • Adlyxin is a drug called lixisenatide.: $702
  • pramlintide is a medication: $1,140
  • Tirzepatide is named after the man.: $486 to $511

Policies, exclusions, requirements for step therapy, and prior authorization vary widely.

It is helpful to know the details of your prescription drug plan.

Injectable medications like glucagon-like peptide-1 receptor agonists are used to treat type 2 diabetes. The person using the drugs gives them daily or weekly.

They may cause side effects like nausea and vomiting.

In addition to medication, a doctor may also recommend lifestyle changes such as following a specific diet and adhering to an Exercise. plan to treat type 2 diabetes.

Dr. Maria S. Prelipcean is a doctor. She works at a medical group. Carol Davila Medical School in Bucharest, Romania, was where Dr. Prelipcean obtained his medical degree. She completed her internal medicine training at the University of Illinois and the University of Alabama in the state of Alabama. Dr. Prelipcean is a Fellow of the American College of Endocrinology and has been named a top doctor in the city many times. She likes to read, travel, and spend time with her family.